Featured Publications
The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications
Peltier M, Verplaetse T, Altemus M, Zakiniaeiz Y, Ralevski E, Mineur Y, Gueorguieva R, Picciotto M, Cosgrove K, Petrakis I, McKee S. The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications. Frontiers In Neuroendocrinology 2024, 73: 101119. PMID: 38184208, PMCID: PMC11185997, DOI: 10.1016/j.yfrne.2023.101119.Peer-Reviewed Original ResearchPosttraumatic stress disorderAlcohol use disorderStress disorderContext of PTSDPTSD/AUDConcurrent posttraumatic stress disorderUnderlying neurobiological mechanismsUse disordersAlcohol-related variablesNeurobiological mechanismsPTSD diagnosisTreatment developmentTreatment implicationsBody of literatureNovel interventionsClinical literatureRole of neurosteroidsDisordersTreatment outcomesYears of researchAlcohol consumptionExogenous pregnenolonePharmacological treatmentBiological variablesAllopregnanolone
2021
Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders
Peltier MR, Verplaetse TL, Mineur YS, Gueorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology 2021, 187: 108499. PMID: 33600842, PMCID: PMC7992136, DOI: 10.1016/j.neuropharm.2021.108499.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStress-related disordersAlcohol useMajor depressive disorderAlcohol-related disordersAlcohol use disorderPosttraumatic stress disorderStress regulation systemComplex comorbiditiesDepressive disorderProblematic alcohol useUse disordersAlcohol misuseTherapeutic potentialTrauma exposureSubstance abuseStress disorderAnxiety disordersDisordersExposure resultsProgestogensNeurosteroidsNegative affectWomenComorbiditiesMale counterparts
2019
The prevalence of substance use disorders among community-based adults with legal problems in the U.S
Moore KE, Oberleitner L, Pittman BP, Roberts W, Verplaetse TL, Hacker RL, Peltier MR, McKee SA. The prevalence of substance use disorders among community-based adults with legal problems in the U.S. Addiction Research & Theory 2019, 28: 165-172. PMID: 32952490, PMCID: PMC7500665, DOI: 10.1080/16066359.2019.1613524.Peer-Reviewed Original ResearchDrug use disordersSubstance use disordersAlcohol use disorderUse disordersAlcohol-related legal problemsSUD diagnosisSystem involvementAUD diagnosisCurrent AUD diagnosisCurrent alcohol use disorderLifetime alcohol use disorderNational prevalence estimatesStimulant use disorderCommunity-based adultsJustice system involvementLifetime AUD diagnosisDUD diagnosesPrevalence estimatesDiagnosisDisordersAdultsDSM-5Continued needIntervention effortsRepresentative U.S. sample
2016
Do they see dead people? Cultural factors and sensitivity in screening for schizophrenia spectrum disorders
Peltier MR, Cosgrove SJ, Ohayagha K, Crapanzano KA, Jones GN. Do they see dead people? Cultural factors and sensitivity in screening for schizophrenia spectrum disorders. Ethnicity And Health 2016, 22: 119-129. PMID: 27306965, DOI: 10.1080/13557858.2016.1196650.Peer-Reviewed Original ResearchConceptsSchizophrenia spectrum disordersAA patientsVisual hallucinationsMini International Neuropsychiatric InterviewHIV outpatient clinicInternational Neuropsychiatric InterviewAfrican AmericansOutpatient clinicNeuropsychiatric InterviewSubsequent diagnosisDisorder modulesSpectrum disorderPsychotic disordersScreening interviewAuditory hallucinationsCurrent studySymptom presentationLogistic regressionPatientsHallucinationsDisordersClinicUnusual experiencesCliniciansDiagnosis