Registered clinical trials investigating ketamine and esketamine for treatment-resistant depression: A systematic review
Brendle M, Ragnhildstveit A, Slayton M, Smart L, Cunningham S, Zimmerman M, Seli P, Gaffrey M, Averill L, Robison R. Registered clinical trials investigating ketamine and esketamine for treatment-resistant depression: A systematic review. Journal Of Psychedelic Studies 2023, 6: 176-187. DOI: 10.1556/2054.2022.00234.Peer-Reviewed Original ResearchTreatment-resistant depressionMontgomery-Asberg Depression Rating ScaleDepression Rating ScaleLate-phase trialsTrial eligibilityPatient characteristicsDrug regimensClinical outcomesResults databaseRegistered trialsClinical trialsTreatment responseEsketaminePharmacological approachesPRISMA guidelinesCombination treatmentMost trialsClinical practiceElectronic registryKetamineSystematic reviewFinal reviewTherapeutic useQualitative synthesisStudy design