2023
“Just fighting for my life to stay alive”: a qualitative investigation of barriers and facilitators to community re-entry among people with opioid use disorder and incarceration histories
Hoffman K, Thompson E, Gaeta Gazzola M, Oberleitner L, Eller A, Madden L, Marcus R, Oberleitner D, Beitel M, Barry D. “Just fighting for my life to stay alive”: a qualitative investigation of barriers and facilitators to community re-entry among people with opioid use disorder and incarceration histories. Addiction Science & Clinical Practice 2023, 18: 16. PMID: 36944998, PMCID: PMC10031976, DOI: 10.1186/s13722-023-00377-y.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidDrug OverdoseHumansMethadoneOpiate Substitution TreatmentOpioid-Related DisordersPrisonersConceptsOpioid use disorderRe-entry experiencesReintegration of peopleSemi-structured qualitative interviewsIncarceration historyExperiences of peoplePerspectives of peopleBasic resourcesThematic analysis approachTransition programCarceral settingsQualitative interviewsLived experienceStable housingStructural barriersSocial challengesFormal transition programQualitative investigationPersistent barriersIncarcerationHistory of incarcerationUse disordersConcrete suggestionsMain themesRe-entry period
2022
The impact of benzodiazepine exposure on treatment retention in an open-access methadone program: A retrospective cohort study
Morford K, Tetrault J, Zhou B, Li F, Gleeson B, Edelman E, Stein M, Barry D, Madden L. The impact of benzodiazepine exposure on treatment retention in an open-access methadone program: A retrospective cohort study. Drug And Alcohol Dependence 2022, 241: 109707. PMID: 36423462, PMCID: PMC9777057, DOI: 10.1016/j.drugalcdep.2022.109707.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBenzodiazepinesHumansMethadoneOpiate Substitution TreatmentOpioid-Related DisordersRetrospective StudiesConceptsBenzodiazepine exposureRetrospective cohort studyKaplan-Meier analysisTreatment retentionCohort studyCox regressionTreatment durationMedian treatment durationMultivariable Cox regressionCohort of patientsOpioid treatment programsOpioid use disorderLog-rank testSame-day accessDrug Administration recommendationsTreatment discontinuationUrine toxicologyMeier analysisMethadone programsUse disordersPatientsAdministration recommendationsTreatment entryTreatment programTreatment barriersEnhancing Use of Medications for Opioid Use Disorder Through External Coaching
Molfenter T, Kim H, Kim JS, Kisicki A, Knudsen HK, Horst J, Brown R, Madden LM, Toy A, Haram E, Jacobson N. Enhancing Use of Medications for Opioid Use Disorder Through External Coaching. Psychiatric Services 2022, 74: 265-271. PMID: 36196533, PMCID: PMC10836327, DOI: 10.1176/appi.ps.202100675.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBuprenorphineHumansNaltrexoneOhioOpiate Substitution TreatmentOpioid-Related DisordersConceptsOpioid use disorderBuprenorphine useControl armUse disordersUse of MOUDUse of medicationsInjectable naltrexoneNaltrexone administrationOutcome measuresCoaching armClinical sitesHealth systemProvider UtilizationTrial periodTreatment agenciesTrialsDelivery modalitiesHealth sitesMedicationsSignificant differencesDisordersArmSimilar patternMOUDNaltrexoneWhat’s in a Name? Terminology Preferences Among Patients Receiving Methadone Treatment
Gazzola MG, Maclean E, Beitel M, Carmichael ID, Cammack KM, Eggert KF, Roehrich T, Madden LM, Jegede O, Zheng X, Bergman E, Barry DT. What’s in a Name? Terminology Preferences Among Patients Receiving Methadone Treatment. Journal Of General Internal Medicine 2022, 38: 653-660. PMID: 36163526, PMCID: PMC9971370, DOI: 10.1007/s11606-022-07813-w.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareBehavior, AddictiveChildCross-Sectional StudiesHumansMaleMethadoneOpiate Substitution TreatmentOpioid-Related DisordersOutpatientsConceptsOpioid use disorderSubstance use disordersMethadone treatmentUse disordersOutpatient methadone treatment programMethadone treatment programsPresenting problemPreferences of patientsTerminology preferencesSubstance-dependent personsCross-sectional surveyAdult patientsMean ageUnivariate analysisMain MeasuresParticipantsPatientsTreatment programKey ResultsWeSubstance abuseSubstance useDisordersSignificant differencesTreatmentDemographic differencesAddiction counselorsA cohort study examining the relationship among housing status, patient characteristics, and retention among individuals enrolled in low-barrier-to-treatment-access methadone maintenance treatment
Gaeta Gazzola M, Carmichael ID, Madden LM, Dasgupta N, Beitel M, Zheng X, Eggert KF, Farnum SO, Barry DT. A cohort study examining the relationship among housing status, patient characteristics, and retention among individuals enrolled in low-barrier-to-treatment-access methadone maintenance treatment. Journal Of Substance Use And Addiction Treatment 2022, 138: 108753. PMID: 35277307, DOI: 10.1016/j.jsat.2022.108753.Peer-Reviewed Original ResearchMeSH KeywordsChronic PainCohort StudiesFemaleHousingHumansMethadoneOpiate Substitution TreatmentRetrospective StudiesConceptsMethadone maintenance treatmentPatient characteristicsChronic painMaintenance treatmentMMT programHousing statusPsychiatric distressCox proportional hazards modelCurrent chronic painPercent of patientsRetrospective chart reviewLog-rank testProportional hazards modelMann-Whitney U testSocial isolationTreatment discontinuationChart reviewCohort studyConsecutive patientsSignificant negative associationHazards modelMeasures of demographicsPatientsSmoking behaviorU test
2021
Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine
Du CX, Shi J, Tetrault JM, Madden LM, Barry DT. Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine. Family Practice 2021, 39: 234-240. PMID: 34893825, PMCID: PMC8947790, DOI: 10.1093/fampra/cmab166.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBuprenorphineChronic PainHumansMedication Therapy ManagementOpiate Substitution TreatmentOpioid-Related DisordersPrimary Health CareConceptsOffice-based opioid treatmentPrimary care providersOpioid use disorderUrine toxicologyOpioid treatmentMore primary care providersOutpatient primary care clinicsChronic pain statusChronic viral hepatitisPrimary care clinicsCommon comorbid conditionsPrimary care characteristicsAddiction treatment settingsHigher median numberEvidence-based treatment modelsOBOT patientsOBOT programOlder patientsPain statusViral hepatitisCommon medicationsRetrospective reviewCare clinicsChronic painComorbid conditionsSuccessful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study
Meteliuk A, Galvez S, Fomenko T, Kalandiia H, Iaryi V, Farnum SO, Islam Z, Altice FL, Madden LM. Successful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study. Journal Of Substance Use And Addiction Treatment 2021, 134: 108619. PMID: 34579978, DOI: 10.1016/j.jsat.2021.108619.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidFemaleHIV InfectionsHumansMaleOpiate Substitution TreatmentOpioid-Related DisordersPilot ProjectsPrimary Health CareSubstance Abuse, IntravenousUkraineConceptsOpioid agonist therapyPrimary care clinicsPrimary care settingOAT coverageAgonist therapyStable patientsCare clinicsSubstance useCare settingsNegative urine drug testsSpecialty addictions treatmentUrine drug testsSymptom Identification ScaleMental health symptomsAddiction treatment clinicsHIV transmissionPrimary careTreatment clinicsOAT patientsBASIS-24PatientsHealth symptomsEmotional labilityAddiction treatmentPilot studyA Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment
DiMeola KA, Haynes J, Barone M, Beitel M, Madden LM, Cutter CJ, Raso A, Gaeta M, Zheng X, Barry DT. A Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment. Journal Of Addiction Medicine 2021, 16: 229-234. PMID: 34145187, PMCID: PMC8678387, DOI: 10.1097/adm.0000000000000877.Peer-Reviewed Original ResearchMeSH KeywordsAdultChronic PainFemaleHumansMaleMethadoneOpiate Substitution TreatmentPain ManagementPilot ProjectsConceptsMethadone maintenance treatmentCurrent pain intensityPain intensityMaintenance treatmentAcute increaseIntervention groupCurrent chronic painMood statesCognitive behavioral therapyMMT clinicsChronic painAcute improvementAcute reductionAcute changesSpecific mood statesPainExergame interventionGroup attendanceUnvalidated measuresMonday-FridayPilot investigationBonferroni correctionPatientsT-testIntervention
2020
A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder
Oberleitner LMS, Madden LM, Muthulingam D, Marcus R, Oberleitner DE, Beitel M, Gaeta M, Tamberelli JF, Barry DT. A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder. Journal Of Substance Use And Addiction Treatment 2020, 121: 108191. PMID: 33357602, PMCID: PMC7770334, DOI: 10.1016/j.jsat.2020.108191.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentTreatment programOpioid treatment programsOpioid use disorderMaintenance treatmentTreatment optionsMethadone maintenanceUse disordersProspective patientsIndividual semi-structured interviewsCounselors' perceptionsTreatment organizationsInterdisciplinary teamCliniciansAddiction counselorsSemi-structured interviewsRapid transitional response to the COVID-19 pandemic by opioid agonist treatment programs in Ukraine
Meteliuk A, Galvez de Leon SJ, Madden LM, Pykalo I, Fomenko T, Filippovych M, Farnum SO, Dvoryak S, Islam ZM, Altice FL. Rapid transitional response to the COVID-19 pandemic by opioid agonist treatment programs in Ukraine. Journal Of Substance Use And Addiction Treatment 2020, 121: 108164. PMID: 33191004, PMCID: PMC7769928, DOI: 10.1016/j.jsat.2020.108164.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBuprenorphineCOVID-19Drug OverdoseHumansMethadoneOpiate Substitution TreatmentOpioid-Related DisordersPatient DropoutsTelemedicineUkraineConceptsOpioid agonist therapyTake-home dosingInterim guidanceShort-term overall mortalityOpioid agonist treatment programPerson clinical encountersOAT deliveryAgonist therapyOverall mortalityCOVID-19 transmissionPatient dropoutOAT patientsNaloxone distributionOverdose educationClinical practiceClinic interactionsTreatment programClinical encountersPatientsCliniciansCOVID-19COVID-19 pandemicOverdosesDosingPrevious yearCorrelates of Homelessness Among Patients in Methadone Maintenance Treatment
Gaeta M, Beitel M, Oberleitner LMS, Oberleitner DE, Madden LM, Tamberelli JF, Barry DT. Correlates of Homelessness Among Patients in Methadone Maintenance Treatment. Medical Care 2020, 58: 1030-1034. PMID: 32925463, PMCID: PMC7668351, DOI: 10.1097/mlr.0000000000001414.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsFemaleHumansIll-Housed PersonsLogistic ModelsMaleMental DisordersMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersSex FactorsSocioeconomic FactorsConceptsOpioid use disorderImportant public health roleLogistic regressionMethadone maintenance treatment programImportant public health issueTreatment-related correlatesCorrelates of homelessnessPercent of patientsMethadone maintenance treatmentFinal logistic regression modelMaintenance treatment programPublic health roleSymptoms of depressionBivariate logistic regressionPublic health issueLogistic regression modelsMaintenance treatmentUse disordersPatientsSignificant independent variablesHealth roleBivariate analysisTreatment programPast monthHigher symptomsThe real‐world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine
Farnum SO, Makarenko I, Madden L, Mazhnaya A, Marcus R, Prokhorova T, Bojko MJ, Rozanova J, Dvoriak S, Islam Z, Altice FL. The real‐world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine. Addiction 2020, 116: 83-93. PMID: 32428276, PMCID: PMC7674222, DOI: 10.1111/add.15115.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidBuprenorphineCohort StudiesFemaleHumansLongitudinal StudiesMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient DropoutsTime FactorsUkraineConceptsOpioid agonist therapyOAT discontinuationAgonist therapyTreatment retentionIndependent predictorsHIV epidemicCost-effective HIV prevention strategyMethadone maintenance treatment patientsObservational longitudinal cohort studySpecialty addictions treatmentBuprenorphine maintenance treatmentHigh dosageHIV prevention strategiesLongitudinal cohort studyOpioid-dependent peopleTreatment discontinuationCohort studyMaintenance treatmentMale sexTreatment patientsPrevention strategiesDiscontinuationYounger ageCenter settingAddiction treatmentOrganizational Facilitators and Barriers to Medication for Opioid Use Disorder Capacity Expansion and Use
Jacobson N, Horst J, Wilcox-Warren L, Toy A, Knudsen HK, Brown R, Haram E, Madden L, Molfenter T. Organizational Facilitators and Barriers to Medication for Opioid Use Disorder Capacity Expansion and Use. The Journal Of Behavioral Health Services & Research 2020, 47: 439-448. PMID: 32347426, PMCID: PMC7578054, DOI: 10.1007/s11414-020-09706-4.Peer-Reviewed Original ResearchMeSH KeywordsBuprenorphineHealth Services AccessibilityHumansInterviews as TopicNaloxoneOpiate Substitution TreatmentOpioid-Related DisordersProgram EvaluationQualitative ResearchUnited States
2019
Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study
Tan J, Altice FL, Madden LM, Zelenev A. Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study. The Lancet HIV 2019, 7: e121-e128. PMID: 31879250, PMCID: PMC7289179, DOI: 10.1016/s2352-3018(19)30373-x.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidHIV InfectionsHumansIncidenceModels, TheoreticalOpiate Substitution TreatmentPrevalenceRiskSubstance Abuse, IntravenousUkraineConceptsOpioid agonist therapyNew HIV infectionsHigh HIV burdenHIV infectionMinistry of HealthOAT coverageAgonist therapyHIV burdenHIV incidenceBuprenorphine maintenance therapyPublic Health CenterMaintenance therapyHIV outcomesHIV prevalenceHIV transmissionMedication procurementHIV epidemicHealth centersHIV preventionTreatment goalsPWIDOAT expansionDisease controlSexual riskInfectionPhysicians’ satisfaction with providing buprenorphine treatment
Knudsen HK, Brown R, Jacobson N, Horst J, Kim JS, Collier E, Starr S, Madden LM, Haram E, Toy A, Molfenter T. Physicians’ satisfaction with providing buprenorphine treatment. Addiction Science & Clinical Practice 2019, 14: 34. PMID: 31446893, PMCID: PMC6709557, DOI: 10.1186/s13722-019-0163-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBuprenorphineFemaleHumansJob SatisfactionMaleMiddle AgedNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPhysiciansPractice Patterns, Physicians'ConceptsBuprenorphine treatmentBaseline Web-based surveyOpioid use disorderGeneral medical practiceStudy of physiciansMedical practiceWaivered physiciansTreatment recommendationsClinical trialsRisk factorsOpioid epidemicImportant treatmentMethodsAs partUse disordersWeb-based surveyPhysician job satisfactionPhysiciansTreatment organizationsBuprenorphineSignificant differencesTreatmentOverall satisfactionSatisfaction itemsStudy measuresLower satisfactionUsing nominal group technique to identify barriers, facilitators, and preferences among patients seeking treatment for opioid use disorder: A needs assessment for decision making support
Muthulingam D, Bia J, Madden LM, Farnum SO, Barry DT, Altice FL. Using nominal group technique to identify barriers, facilitators, and preferences among patients seeking treatment for opioid use disorder: A needs assessment for decision making support. Journal Of Substance Use And Addiction Treatment 2019, 100: 18-28. PMID: 30898324, PMCID: PMC6432946, DOI: 10.1016/j.jsat.2019.01.019.Peer-Reviewed Original ResearchConceptsOpioid use disorderNominal group techniquePharmacologic therapyUse disordersSyringe exchange programsIndividual-level barriersEvidence-based interventionsAddiction treatment centersEvidence-based strategiesOUD treatmentPharmacologic treatmentSpecific medicationsTreatment optionsPharmacologic propertiesMedicationsDecision aidPatient considerationsSide effectsTreatment centersOpioid crisisSpecific knowledge gapsGroup techniqueDecision aid developmentTreatmentTherapyElectronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment
Baldassarri SR, Fiellin DA, Savage ME, Madden LM, Beitel M, Dhingra LK, Fucito L, Camenga D, Bollampally P, Barry DT. Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment. Drug And Alcohol Dependence 2019, 197: 37-41. PMID: 30769264, PMCID: PMC6637405, DOI: 10.1016/j.drugalcdep.2018.12.012.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid agonist therapyCurrent cigarette smokingCigarette smokingEC useHigher oddsFormer smokersLower oddsPsychiatric distressPast cigarette smokingElectronic cigarette useAgonist therapyCurrent smokersBuprenorphine treatmentChronic painTobacco useNicotine dependenceUse disordersSmokingCigarette useMultivariate analysisElectronic cigarettesSmokersCigarettesMultivariate modelPharmacotherapy, Resource Needs, and Physician Recruitment Practices in Substance Use Disorder Treatment Programs
Knudsen HK, Brown R, Jacobson N, Horst J, Kim JS, Collier E, Starr S, Madden LM, Haram E, Molfenter T. Pharmacotherapy, Resource Needs, and Physician Recruitment Practices in Substance Use Disorder Treatment Programs. Journal Of Addiction Medicine 2019, 13: 28-34. PMID: 30095565, PMCID: PMC6349477, DOI: 10.1097/adm.0000000000000441.Peer-Reviewed Original ResearchConceptsOpioid use disorderTreatment programSubstance use disorder treatment programsImplementation of pharmacotherapyEffective pharmacological treatmentAvailability of buprenorphineTreatment organizationsDisorder treatment programsTablet naltrexoneInjectable naltrexoneAvailable medicationsPharmacological treatmentLifesaving treatmentPhysician outreachUse disordersPharmacotherapyMean numberTreatment slotsMedicationsNaltrexonePrescribersCurrent useResource needsPhysician recruitmentTreatment
2018
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot studyExperiences of Burnout among Drug Counselors in A Large Opioid Treatment Program: A Qualitative Investigation
Beitel M, Oberleitner L, Muthulingam D, Oberleitner D, Madden LM, Marcus R, Eller A, Bono MH, Barry DT. Experiences of Burnout among Drug Counselors in A Large Opioid Treatment Program: A Qualitative Investigation. Substance Abuse 2018, 39: 211-217. PMID: 29522381, DOI: 10.1080/08897077.2018.1449051.Peer-Reviewed Original ResearchMeSH KeywordsAdultBurnout, ProfessionalCounselorsFemaleHumansMaleMiddle AgedOpiate Substitution TreatmentQualitative ResearchQuality ImprovementConceptsExperience of burnoutDrug counselorsTreatment programJob-related demandsIndividual semi-structured interviewsWork engagementCounselor burnoutBurnoutCounselor feedbackPhysiological symptomsSemi-structured interviewsCounselorsQualitative investigationParticipantsPossible experienceSystem-level changesCounselor descriptionsExperienceProgram settingsOpioid treatment programsTreatment gapMultidisciplinary teamEngagementProgramTranscribed