2021
Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics): A cluster-randomized type 3 hybrid effectiveness-implementation trial
Becker SJ, Murphy CM, Hartzler B, Rash CJ, Janssen T, Roosa M, Madden LM, Garner BR. Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics): A cluster-randomized type 3 hybrid effectiveness-implementation trial. Addiction Science & Clinical Practice 2021, 16: 61. PMID: 34635178, PMCID: PMC8505014, DOI: 10.1186/s13722-021-00268-0.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidHumansMotivationOpioid-Related DisordersReimbursement, IncentiveResearch DesignUnited StatesConceptsOpioid treatment programsOpioid use disorderPatient outcomesTreatment programUse disordersContingency managementPutative mediatorsHybrid effectiveness-implementation trialOpioid-related problemsEffectiveness-implementation trialImplementation of CMImplementation outcomesUrgent public health needEvidence-based treatmentsUnit of randomizationPublic health emergencyPublic health needsOpioid abstinenceCM exposurePatient surveyEffective behavioral interventionsClinical trialsProvider surveySession audio recordingsHealth needs
2020
The Balanced Opioid Initiative: protocol for a clustered, sequential, multiple-assignment randomized trial to construct an adaptive implementation strategy to improve guideline-concordant opioid prescribing in primary care
Quanbeck A, Almirall D, Jacobson N, Brown RT, Landeck JK, Madden L, Cohen A, Deyo BMF, Robinson J, Johnson RA, Schumacher N. The Balanced Opioid Initiative: protocol for a clustered, sequential, multiple-assignment randomized trial to construct an adaptive implementation strategy to improve guideline-concordant opioid prescribing in primary care. Implementation Science 2020, 15: 26. PMID: 32334632, PMCID: PMC7183389, DOI: 10.1186/s13012-020-00990-4.Peer-Reviewed Original ResearchConceptsOpioid prescribing practicesPrimary care clinicsPractice facilitationPrescribing practicesPrimary careOpioid prescribingMonth 3Primary outcomeCare clinicsDifferent primary care clinicsDiverse primary care clinicsHybrid type 3Study's primary outcomeDifferent clinical settingsPrimary aimCost-effective sequenceOpioid misuseEvidence-based practiceMonth 21Study's primary aimClinical guidelinesImplementation strategiesOverdose deathsDesignThe studyAdaptive implementation strategy
2018
A randomized matched-pairs study of feasibility, acceptability, and effectiveness of systems consultation: a novel implementation strategy for adopting clinical guidelines for Opioid prescribing in primary care
Quanbeck A, Brown RT, Zgierska AE, Jacobson N, Robinson JM, Johnson RA, Deyo BM, Madden L, Tuan WJ, Alagoz E. A randomized matched-pairs study of feasibility, acceptability, and effectiveness of systems consultation: a novel implementation strategy for adopting clinical guidelines for Opioid prescribing in primary care. Implementation Science 2018, 13: 21. PMID: 29370813, PMCID: PMC5784593, DOI: 10.1186/s13012-018-0713-1.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidChronic PainDelivery of Health CareEvidence-Based PracticeFemaleFocus GroupsGuideline AdherenceHumansInterviews as TopicMaleOpioid-Related DisordersPractice Guidelines as TopicPractice Patterns, Physicians'Primary Health CareQualitative ResearchReferral and ConsultationResearch DesignConceptsOpioid prescribingIntervention clinicsClinical guidelinesPrimary careMorphine equivalent daily doseSafe opioid prescribingPercentage of patientsPrimary care clinicsMental health screenUrine drug testsRE-AIM frameworkDiscrete implementation strategiesMatched-pair studyInnovative implementation strategyDaily doseCare clinicsChronic painAcademic detailingTreatment agreementsHealth screenChronic conditionsImplementation strategiesOpioid abuseControl clinicsMixed-method evaluation
2017
Test of a workforce development intervention to expand opioid use disorder treatment pharmacotherapy prescribers: protocol for a cluster randomized trial
Molfenter T, Knudsen HK, Brown R, Jacobson N, Horst J, Van Etten M, Kim JS, Haram E, Collier E, Starr S, Toy A, Madden L. Test of a workforce development intervention to expand opioid use disorder treatment pharmacotherapy prescribers: protocol for a cluster randomized trial. Implementation Science 2017, 12: 135. PMID: 29141653, PMCID: PMC5688699, DOI: 10.1186/s13012-017-0665-x.Peer-Reviewed Original ResearchConceptsOpioid use disorderAddiction treatment fieldPrevalence of OUDSubstantial public health significanceOpioid misuse epidemicExtended-release naltrexonePrimary treatment outcomeEvidence-based pharmacotherapyAddiction treatment workforceSignificant health issuePublic health significanceAddiction treatment providersNaltrexone patientsNon-medical useOUD pharmacotherapyTreatment fieldOUD patientsBuprenorphine patientsPrescription opioidsCluster RCTIntervention periodTreatment outcomesImplementation interventionsOverdose deathsUse disorders