2014
A Regulatory Network of Drosophila Germline Stem Cell Self-Renewal
Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N. A Regulatory Network of Drosophila Germline Stem Cell Self-Renewal. Developmental Cell 2014, 28: 459-473. PMID: 24576427, PMCID: PMC3998650, DOI: 10.1016/j.devcel.2014.01.020.Peer-Reviewed Original ResearchConceptsGermline stem cellsSelf-renewal factorsDrosophila female germline stem cellsStem cellsDifferent stem cell lineagesLarge-scale RNAi screenFemale germline stem cellsLoss of Set1Stem Cell Self-RenewalSpecific genetic networksHistone methyltransferase Set1Stem cell identityCell fate decisionsStem cell lineagesCell Self-RenewalSelf-renewal genesRNAi screenDistinct fatesFate decisionsGSC maintenanceCell identityCell fateRegulatory networksGenetic networksNeural stem cells
2002
SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila
Zallen JA, Cohen Y, Hudson AM, Cooley L, Wieschaus E, Schejter ED. SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila. Journal Of Cell Biology 2002, 156: 689-701. PMID: 11854309, PMCID: PMC2174092, DOI: 10.1083/jcb.200109057.Peer-Reviewed Original ResearchMeSH KeywordsActin-Related Protein 2Actin-Related Protein 3ActinsAmino Acid SequenceAnimalsAxonsBase SequenceBlastodermBrainCytoplasmCytoskeletal ProteinsDNA, ComplementaryDrosophilaDrosophila ProteinsGenes, InsectHumansInsect ProteinsMicrofilament ProteinsMolecular Sequence DataMorphogenesisMutagenesisOogenesisOvumProteinsSequence Homology, Amino AcidWiskott-Aldrich Syndrome ProteinConceptsWiskott-Aldrich syndrome proteinArp2/3 complexAdult eye morphologyScar/WAVECell fate decisionsActin-rich structuresCell biological eventsCortical filamentous actinCell morphologyDrosophila developmentMultiple cell typesNormal cell morphologySCAR homologueFate decisionsSyndrome proteinActin structuresFilamentous actinActin polymerizationCell shapeMorphological eventsCytoplasmic organizationEye morphologyBiological eventsCell typesDevelopmental requirements