2011
Reversible response of protein localization and microtubule organization to nutrient stress during Drosophila early oogenesis
Shimada Y, Burn KM, Niwa R, Cooley L. Reversible response of protein localization and microtubule organization to nutrient stress during Drosophila early oogenesis. Developmental Biology 2011, 355: 250-262. PMID: 21570389, PMCID: PMC3118931, DOI: 10.1016/j.ydbio.2011.04.022.Peer-Reviewed Original ResearchConceptsEgg chambersNutrient stressIntercellular transportMT reorganizationNutrient availabilityNurse cellsPutative RNA binding proteinMT-dependent mannerRNA binding proteinYpsilon SchachtelDrosophila oogenesisProcessing bodiesProtein localizationEarly oogenesisNutrient deprivationMicrotubule organizationMetabolic checkpointCytoplasmic componentsAnimal oocytesStress responseYolk uptakeBinding proteinPrevitellogenic stageOogenesisIndependent mechanisms
2003
Drosophila filamin is required for follicle cell motility during oogenesis
Sokol NS, Cooley L. Drosophila filamin is required for follicle cell motility during oogenesis. Developmental Biology 2003, 260: 260-272. PMID: 12885568, DOI: 10.1016/s0012-1606(03)00248-3.Peer-Reviewed Original ResearchConceptsGermline cystsFilamin proteinsCell motilityFollicle cell morphogenesisActin-binding domainActin binding proteinsFilamin repeatsDrosophila ovaryFilamin functionCell morphogenesisDrosophila filaminFilamin familyCell movementProtein 120Cell shapeBorder cellsCell locomotionFollicle cellsBinding proteinPoint mutationsInitial encapsulationProteinMorphogenesisReduced expressionFilamin
1994
Profilin mutations disrupt multiple actin-dependent processes during Drosophila development
Verheyen E, Cooley L. Profilin mutations disrupt multiple actin-dependent processes during Drosophila development. Development 1994, 120: 717-728. PMID: 7600952, DOI: 10.1242/dev.120.4.717.Peer-Reviewed Original ResearchConceptsSmall actin binding proteinsEmbryonic lethal phenotypeActin-dependent processesActin binding proteinsActin filament bundlesDrosophila profilinProfilin mutationDrosophila developmentMulticellular organismsViable allelesBristle formationLethal phenotypeActin assemblyProfilin functionSubcellular localizationGenomic deletionsBinding proteinCell migrationCell typesProfilinFilament bundlesOogenesisAbnormal regulationBinucleate cellsDeletion