Feasibility and Sensitivity of Saliva GeneXpert MTB/RIF Ultra for Tuberculosis Diagnosis in Adults in Uganda
Byanyima P, Kaswabuli S, Musisi E, Nabakiibi C, Zawedde J, Sanyu I, Sessolo A, Andama A, Worodria W, Huang L, Davis JL. Feasibility and Sensitivity of Saliva GeneXpert MTB/RIF Ultra for Tuberculosis Diagnosis in Adults in Uganda. Microbiology Spectrum 2022, 10: e00860-22. PMID: 36154664, PMCID: PMC9603304, DOI: 10.1128/spectrum.00860-22.Peer-Reviewed Original ResearchConceptsGeneXpert MTB/RIF UltraMTB/RIF UltraXpert UltraTB diagnosisMolecular testingHigh TB burden settingsCulture-confirmed TB casesSaliva samplesTB diagnostic evaluationActive tuberculosis diseaseProspective observational studyActive TB diagnosisCause of morbidityAcid-fast bacilliComposite reference standardReference standardCase-only studySingle saliva sampleWorld Health OrganizationSpot sputumTB evaluationConsecutive adultsTB casesBurden settingsOutpatient department