Molecular Typing Demonstrating Transmission of Gram-Negative Rods in a Neonatal Intensive Care Unit in the Absence of a Recognized Epidemic
Almuneef M, Baltimore R, Farrel P, Reagan-Cirincione P, Dembry L. Molecular Typing Demonstrating Transmission of Gram-Negative Rods in a Neonatal Intensive Care Unit in the Absence of a Recognized Epidemic. Clinical Infectious Diseases 2000, 32: 220-227. PMID: 11170911, DOI: 10.1086/318477.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial Typing TechniquesCross InfectionDNA, BacterialDrug Resistance, MicrobialElectrophoresisFecesFemaleGenotypeGentamicinsGram-Negative Aerobic Rods and CocciGram-Negative Bacterial InfectionsHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMicrobial Sensitivity TestsConceptsNeonatal intensive care unitIntensive care unitShared strainsCare unitMolecular typing techniquesRectal swab culturesColonization of infantsGentamicin-resistant strainsWeeks of ageTyping techniquesAntibiotic treatmentAntibiotic useSwab culturesGram-negative rodsGentamicin susceptibilityInfantsTotal daysOutbreak investigationIdentical strainsNegative rodsUnique strainsHigh rateContour-clamped homogeneous electric field electrophoresisAdmissionGentamicin