2020
Intestinal metaplasia around the gastroesophageal junction is frequently associated with antral reactive gastropathy: implications for carcinoma at the gastroesophageal junction
Vyas M, Celli R, Singh M, Patel N, Aslanian HR, Boffa D, Deng Y, Ciarleglio MM, Laine L, Jain D. Intestinal metaplasia around the gastroesophageal junction is frequently associated with antral reactive gastropathy: implications for carcinoma at the gastroesophageal junction. Human Pathology 2020, 105: 67-73. PMID: 32941964, PMCID: PMC11152084, DOI: 10.1016/j.humpath.2020.08.007.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsBile refluxIntestinal metaplasiaReactive gastropathyGEJ regionMucosal injuryMucosal changesGastroesophageal junctionAntral intestinal metaplasiaDistal esophageal adenocarcinomaDetailed clinical historySex-matched patientsGastric antral biopsiesAnti-inflammatory drugsGastric bile refluxMucosal inflammationProximal stomachDistal esophagusMedication usePancreatic metaplasiaPathology databaseProximal gastricAntral biopsiesClinical historyGastric biopsies
2013
Natural history of acute upper GI bleeding due to tumours: short‐term success and long‐term recurrence with or without endoscopic therapy
Sheibani S, Kim JJ, Chen B, Park S, Saberi B, Keyashian K, Buxbaum J, Laine L. Natural history of acute upper GI bleeding due to tumours: short‐term success and long‐term recurrence with or without endoscopic therapy. Alimentary Pharmacology & Therapeutics 2013, 38: 144-150. PMID: 23710797, DOI: 10.1111/apt.12347.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal bleedingEndoscopic therapyHaemodynamic instabilityMalignant tumorsBiopsy-proven malignant tumorsAcute upper GISubstantial blood lossLong-term recurrenceYears of ageInitial haemostasisRepeat hospitalisationActive bleedingGastrointestinal bleedingIndex hospitalisationEndoscopic findingsMetastatic diseaseUpper endoscopyBlood lossConsecutive patientsEndoscopic treatmentUpper GIEndoscopy databaseRisk factorsPatientsMultivariate analysis