Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud
Karihaloo A, Karumanchi S, Barasch J, Jha V, Nickel C, Yang J, Grisaru S, Bush K, Nigam S, Rosenblum N, Sukhatme V, Cantley L. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 12509-12514. PMID: 11606725, PMCID: PMC60084, DOI: 10.1073/pnas.221205198.Peer-Reviewed Original ResearchCell Surface Glypicans Are Low-Affinity Endostatin Receptors
Karumanchi S, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai J, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen R, Lander A, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme V. Cell Surface Glypicans Are Low-Affinity Endostatin Receptors. Molecular Cell 2001, 7: 811-822. PMID: 11336704, DOI: 10.1016/s1097-2765(01)00225-8.Peer-Reviewed Original ResearchConceptsHeparan sulfate glycosaminoglycansPotent anti-angiogenic proteinCell surface proteoglycansBranching morphogenesisEndothelial cellsGenetic studiesGlypicansExpression cloningSurface proteoglycansAntisense experimentsCell surfaceAnti-angiogenic proteinEndothelial cell surfaceLow-affinity receptorsSulfate glycosaminoglycansEndostatin bindingCellsReceptorsMorphogenesisEndostatin activityCloningProteinEndostatinBindingProteoglycans