Epigenetics and Signaling Pathways in Glaucoma
Gauthier AC, Liu J. Epigenetics and Signaling Pathways in Glaucoma. BioMed Research International 2017, 2017: 5712341. PMID: 28210622, PMCID: PMC5292191, DOI: 10.1155/2017/5712341.Peer-Reviewed Original ResearchConceptsPotential new therapeutic targetGeneration of fibrosisNovel therapeutic agentsNew therapeutic targetsAqueous humor drainageProapoptotic gene expressionRetinal neuronsIrreversible blindnessCommon causeHuman trialsTherapeutic targetAnimal modelsTrabecular meshworkTherapeutic agentsNeurodegenerative diseasesProsurvival factorBcl-2Rho-kinaseGlaucomaSignaling pathwaysPathway membersMAP kinaseGene expressionPathwayPreliminary success