The familial aggregation of cannabis use disorders
Merikangas KR, Li JJ, Stipelman B, Yu K, Fucito L, Swendsen J, Zhang H. The familial aggregation of cannabis use disorders. Addiction 2009, 104: 622-629. PMID: 19335660, PMCID: PMC2794246, DOI: 10.1111/j.1360-0443.2008.02468.x.Peer-Reviewed Original ResearchConceptsSpouses of probandsFirst-degree relativesCannabis use disorderLife-time historyUse disordersAnxiety disordersAlcohol abuse/dependenceFamilial aggregationAbuse/dependenceFirst-degree adult relativesComorbid moodElevated riskFamily-based approachPsychiatric clinicAffective disordersAlcohol dependencePsychiatric conditionsFamily study methodDrug abuseFamilial factorsDisordersAdult relativesCannabisFamilial transmissionGenetic factors