Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density
Calvocoressi L, Uchio E, Ko J, Radhakrishnan K, Aslan M, Concato J. Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. Journal Of Investigative Medicine 2018, 66: 1142. PMID: 30297390, DOI: 10.1136/jim-2018-000804.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overBiomarkers, TumorHumansMaleMicrovesselsNeoplasm InvasivenessProstatic NeoplasmsProto-Oncogene Proteins c-bcl-2Tumor Suppressor Protein p53ConceptsGleason scoreMicrovessel densityProstate cancerBcl-2Prostate-specific antigen levelProstate cancer deathAdvanced prostate cancerAggressive prostate cancerB-cell lymphoma 2Prostate cancer aggressivenessPositive Bcl-2Impact of p53Cell lymphoma 2Anatomic stageMen 70Adjusted ORsAntigen levelsCategories of ageCancer deathElderly menDisease progressionImmunohistochemical stainingStudy populationCancer aggressivenessProstate tumors