2019
Mendelian randomization provides support for obesity as a risk factor for meningioma
Takahashi H, Cornish AJ, Sud A, Law PJ, Disney-Hogg L, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Schildkraut JM, Simon M, Bondy M, Wrensch M, Wiemels JL, Claus EB, Turnbull C, Houlston RS. Mendelian randomization provides support for obesity as a risk factor for meningioma. Scientific Reports 2019, 9: 309. PMID: 30670737, PMCID: PMC6343031, DOI: 10.1038/s41598-018-36186-6.Peer-Reviewed Original ResearchConceptsRisk of meningiomaMeningioma riskObesity-related traitsLipoprotein cholesterolBlood pressureRisk factorsOdds ratioLow-density lipoprotein cholesterolHigh-density lipoprotein cholesterolMendelian randomizationCause of meningiomaGenetic instrumentsDiastolic blood pressureEpidemiological observational studiesSystolic blood pressureBody mass indexBody fat percentageWaist circumferenceTotal cholesterolMass indexObservational studyMeningioma patientsMeningiomasBasal metabolic rateObesity
2014
Endogenous and exogenous hormone exposure and the risk of meningioma in men.
Schildkraut JM, Calvocoressi L, Wang F, Wrensch M, Bondy ML, Wiemels JL, Claus EB. Endogenous and exogenous hormone exposure and the risk of meningioma in men. Journal Of Neurosurgery 2014, 120: 820-6. PMID: 24484233, PMCID: PMC4386752, DOI: 10.3171/2013.12.jns131170.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexHumansMaleMeningeal NeoplasmsMeningiomaMiddle AgedPrevalenceRiskSoybean ProteinsConceptsBody mass indexMeningioma riskOdds ratioHigher body mass indexExogenous hormone exposureMultivariate logistic regressionRelated risk factorsConfidence intervalsRisk of meningiomaPrevalence of exposureConsiderable morbidityMale patientsMass indexRisk factorsEndogenous estrogensReduced riskHormonal factorsHormone exposureIntracranial meningiomasExogenous exposureMeningiomasLogistic regressionUse of soyMenRisk
2012
Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females.
Claus EB, Calvocoressi L, Bondy ML, Wrensch M, Wiemels JL, Schildkraut JM. Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. Journal Of Neurosurgery 2012, 118: 649-56. PMID: 23101448, PMCID: PMC3756881, DOI: 10.3171/2012.9.jns12811.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAgedBody Mass IndexBreast FeedingConnecticutContraceptives, OralEstrogen Replacement TherapyFemaleHumansMassachusettsMenarcheMeningeal NeoplasmsMeningiomaMenopauseMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioParityRegistriesReproductive HistoryRisk AssessmentRisk FactorsSan FranciscoSmokingTexasConceptsBody mass indexMeningioma riskMass indexIntracranial meningiomasExogenous hormone useHormone replacement therapyRisk of meningiomaYears of ageCurrent useResidents of ConnecticutHormone medicationWomen 29Postmenopausal womenPremenopausal womenCurrent smokingFertility medicationsOral contraceptivesHormone useMenstrual factorsSignificant positive associationCigarette smokingReplacement therapyRisk factorsReproductive factorsSignificant elevation