2022
Pleiotropic MLLT10 variation confers risk of meningioma and estrogen-mediated cancers
Walsh KM, Zhang C, Calvocoressi L, Hansen HM, Berchuck A, Schildkraut JM, Bondy ML, Wrensch M, Wiemels JL, Claus EB. Pleiotropic MLLT10 variation confers risk of meningioma and estrogen-mediated cancers. Neuro-Oncology Advances 2022, 4: vdac044. PMID: 35702670, PMCID: PMC9187056, DOI: 10.1093/noajnl/vdac044.Peer-Reviewed Original ResearchRisk of meningiomaOvarian cancerBreast cancerER- breast cancerEstrogen receptor statusBody mass indexFemale breast cancerRisk of tumorsReceptor statusMass indexEstrogenic mechanismsHormonal factorsGenome-wide association studiesMeningiomasNormal meningesCancerMinor alleleCase-control datasetUK BiobankExpression quantitative trait lociMeningesRiskTumorsBreastAdiposity traits
2016
MNGO-11. REPORT FROM THE MENINGIOMA CONSORTIUM: CONFIRMATION OF A MENINGIOMA RISK LOCUS AT 10p12
Claus E, Calvocoressi L, Schildkraut J, Walsh K, Hansen H, Smirnov I, McCoy L, Lu L, Ma X, Bondy M, Wrensch M, Wiemels J. MNGO-11. REPORT FROM THE MENINGIOMA CONSORTIUM: CONFIRMATION OF A MENINGIOMA RISK LOCUS AT 10p12. Neuro-Oncology 2016, 18: vi103-vi103. DOI: 10.1093/neuonc/now212.432.Peer-Reviewed Original ResearchOdds ratioMeningioma riskMeningioma casesPrimary brain tumorsPopulation-based controlsCase/control studyNon-Hispanic CaucasiansAllele odds ratioGenome-wide association studiesKaiser Permanente Research ProgramSpinal cordSuch lesionsBrain tumorsControl studyConfidence intervalsFirst genome-wide association studyMeningiomasTumorsRisk lociUnited StatesSusceptibility lociRisk
2014
Endogenous and exogenous hormone exposure and the risk of meningioma in men.
Schildkraut JM, Calvocoressi L, Wang F, Wrensch M, Bondy ML, Wiemels JL, Claus EB. Endogenous and exogenous hormone exposure and the risk of meningioma in men. Journal Of Neurosurgery 2014, 120: 820-6. PMID: 24484233, PMCID: PMC4386752, DOI: 10.3171/2013.12.jns131170.Peer-Reviewed Original ResearchConceptsBody mass indexMeningioma riskOdds ratioHigher body mass indexExogenous hormone exposureMultivariate logistic regressionRelated risk factorsConfidence intervalsRisk of meningiomaPrevalence of exposureConsiderable morbidityMale patientsMass indexRisk factorsEndogenous estrogensReduced riskHormonal factorsHormone exposureIntracranial meningiomasExogenous exposureMeningiomasLogistic regressionUse of soyMenRisk
2012
Cigarette Smoking and Risk of Meningioma: The Effect of Gender
Claus EB, Walsh KM, Calvocoressi L, Bondy ML, Schildkraut JM, Wrensch M, Wiemels JL. Cigarette Smoking and Risk of Meningioma: The Effect of Gender. Cancer Epidemiology Biomarkers & Prevention 2012, 21: 943-950. PMID: 22473761, PMCID: PMC3613227, DOI: 10.1158/1055-9965.epi-11-1059.Peer-Reviewed Original ResearchConceptsCigarette smokingIntracranial meningiomasCase-control studyRisk of meningiomaDuration of useEffect of genderPast smokersMenopausal statusHormonal etiologyFemale casesMale casesMeningioma riskReduced riskElevated riskMeningioma casesSmokingCase statusGreater riskSimilar findingsMeningiomasRiskAdditional investigationNumber of studiesInconsistent findingsWomenDental x‐rays and risk of meningioma
Claus EB, Calvocoressi L, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M. Dental x‐rays and risk of meningioma. Cancer 2012, 118: 4530-4537. PMID: 22492363, PMCID: PMC3396782, DOI: 10.1002/cncr.26625.Peer-Reviewed Original ResearchConceptsRisk of meningiomaDental X-raysModifiable risk factorsIntracranial meningiomasRisk factorsAge 20Population-based case-control studyMain outcome measuresPrimary brain tumorsCase-control studyGreater frequencyPanorex filmsTumor locationBitewing examinationOutcome measuresElevated riskBrain tumorsControl groupMeningiomasYounger ageRadiation exposureAge 10AgePatientsRisk