2019
Mendelian randomization provides support for obesity as a risk factor for meningioma
Takahashi H, Cornish AJ, Sud A, Law PJ, Disney-Hogg L, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Schildkraut JM, Simon M, Bondy M, Wrensch M, Wiemels JL, Claus EB, Turnbull C, Houlston RS. Mendelian randomization provides support for obesity as a risk factor for meningioma. Scientific Reports 2019, 9: 309. PMID: 30670737, PMCID: PMC6343031, DOI: 10.1038/s41598-018-36186-6.Peer-Reviewed Original ResearchConceptsRisk of meningiomaMeningioma riskObesity-related traitsLipoprotein cholesterolBlood pressureRisk factorsOdds ratioLow-density lipoprotein cholesterolHigh-density lipoprotein cholesterolMendelian randomizationCause of meningiomaGenetic instrumentsDiastolic blood pressureEpidemiological observational studiesSystolic blood pressureBody mass indexBody fat percentageWaist circumferenceTotal cholesterolMass indexObservational studyMeningioma patientsMeningiomasBasal metabolic rateObesity
2016
MNGO-11. REPORT FROM THE MENINGIOMA CONSORTIUM: CONFIRMATION OF A MENINGIOMA RISK LOCUS AT 10p12
Claus E, Calvocoressi L, Schildkraut J, Walsh K, Hansen H, Smirnov I, McCoy L, Lu L, Ma X, Bondy M, Wrensch M, Wiemels J. MNGO-11. REPORT FROM THE MENINGIOMA CONSORTIUM: CONFIRMATION OF A MENINGIOMA RISK LOCUS AT 10p12. Neuro-Oncology 2016, 18: vi103-vi103. DOI: 10.1093/neuonc/now212.432.Peer-Reviewed Original ResearchOdds ratioMeningioma riskMeningioma casesPrimary brain tumorsPopulation-based controlsCase/control studyNon-Hispanic CaucasiansAllele odds ratioGenome-wide association studiesKaiser Permanente Research ProgramSpinal cordSuch lesionsBrain tumorsControl studyConfidence intervalsFirst genome-wide association studyMeningiomasTumorsRisk lociUnited StatesSusceptibility lociRisk
2014
Endogenous and exogenous hormone exposure and the risk of meningioma in men.
Schildkraut JM, Calvocoressi L, Wang F, Wrensch M, Bondy ML, Wiemels JL, Claus EB. Endogenous and exogenous hormone exposure and the risk of meningioma in men. Journal Of Neurosurgery 2014, 120: 820-6. PMID: 24484233, PMCID: PMC4386752, DOI: 10.3171/2013.12.jns131170.Peer-Reviewed Original ResearchConceptsBody mass indexMeningioma riskOdds ratioHigher body mass indexExogenous hormone exposureMultivariate logistic regressionRelated risk factorsConfidence intervalsRisk of meningiomaPrevalence of exposureConsiderable morbidityMale patientsMass indexRisk factorsEndogenous estrogensReduced riskHormonal factorsHormone exposureIntracranial meningiomasExogenous exposureMeningiomasLogistic regressionUse of soyMenRisk