Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods
Han L, Kim N, Brandt C, Allore HG. Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods. Annals Of Epidemiology 2011, 22: 9-16. PMID: 22037381, PMCID: PMC4054866, DOI: 10.1016/j.annepidem.2011.10.004.Peer-Reviewed Original ResearchConceptsDepression-related diagnosisAntidepressant useDepression symptomsOlder personsPropensity scoreHopkins Verbal Learning TestHypertensive menAntidepressant medicationIndication biasVerbal Learning TestMedical recordsPotential confoundingCumulative exposureOlder menCognitive impairmentMemory deficitsCognitive deficitsMultiple linear regressionLinear regressionLearning TestApparent associationScoresSymptomsDiagnosisIndicationsAntidepressant Use and Cognitive Functioning in Older Medical Patients With Major or Minor Depression
Han L, McCusker J, Cole M, apek R, Abrahamowicz M. Antidepressant Use and Cognitive Functioning in Older Medical Patients With Major or Minor Depression. Journal Of Clinical Psychopharmacology 2011, 31: 429-435. PMID: 21694621, PMCID: PMC3558972, DOI: 10.1097/jcp.0b013e318221b2f8.Peer-Reviewed Original ResearchConceptsOlder medical patientsAntidepressant useMinor depressionMedical patientsAntidepressant medicationMini-Mental State Examination scoreHamilton Depression Rating ScaleMini-Mental State ExaminationProvincial prescription databasePsychotropic drug useDepression Rating ScaleAcute care hospitalsState Examination scoreComplex medical conditionsLong-term cognitive effectsSignificant cognitive impairmentSmall cognitive improvementsAntidepressant prescriptionsCare hospitalConcomitant benzodiazepinesMedical inpatientsPrescription databaseAntidepressant agentsDepression diagnosisMajor depression