2014
Antihypertensive Medications and Serious Fall Injuries in a Nationally Representative Sample of Older Adults
Tinetti ME, Han L, Lee DS, McAvay GJ, Peduzzi P, Gross CP, Zhou B, Lin H. Antihypertensive Medications and Serious Fall Injuries in a Nationally Representative Sample of Older Adults. JAMA Internal Medicine 2014, 174: 588-595. PMID: 24567036, PMCID: PMC4136657, DOI: 10.1001/jamainternmed.2013.14764.Peer-Reviewed Original ResearchConceptsSerious fall injuriesAdjusted hazard ratioAntihypertensive medicationsMultiple chronic conditionsFall injuriesAntihypertensive groupHazard ratioOlder adultsChronic conditionsAntihypertensive medication classesStandardized daily doseAntihypertensive medication useCommunity-living adultsPropensity score adjustmentTraumatic brain injuryHealthy older adultsMedication intensityCardiovascular eventsMedication classesDaily doseHip fractureMedication useNationally Representative SampleHead injuryBrain injuryAnti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions
Tinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin H. Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions. PLOS ONE 2014, 9: e90733. PMID: 24614535, PMCID: PMC3948696, DOI: 10.1371/journal.pone.0090733.Peer-Reviewed Original ResearchConceptsMultiple chronic conditionsAnti-hypertensive treatmentCardiovascular eventsAnti-hypertensive medicationsHigh-intensity groupChronic conditionsOlder adultsHazard ratioPropensity scoreIntensity groupStandardized daily doseCommunity-living participantsPropensity score adjustmentCV eventsMedication intensityLess comorbidityDaily doseRandomized trialsMAIN OUTCOMERepresentative cohortScore adjustmentSurvey cohortRCT resultsCohortMortality
2007
Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men
Agostini JV, Tinetti ME, Han L, Peduzzi P, Foody JM, Concato J. Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men. Journal Of General Internal Medicine 2007, 22: 1661-1667. PMID: 17899299, PMCID: PMC2219823, DOI: 10.1007/s11606-007-0388-9.Peer-Reviewed Original ResearchConceptsNon-cardiovascular outcomesAntihypertensive medication useAntihypertensive medicationsMedication useAdverse effectsOlder menCommunity-living older menVeterans Affairs primary care clinicsEpidemiologic Studies-Depression scoreOlder adultsMultiple antihypertensive medicationsPhysical performancePrimary care clinicsDrug adverse effectsRoutine clinical practiceCES-D scoresHigh cumulative exposureRelated adverse effectsTrail Making BMedication intensityTest Part BHypertensive menCerebrovascular effectsCohort studyBlood pressure