Featured Publications
Transitions Between Frailty States Among Community-Living Older Persons
Gill TM, Gahbauer EA, Allore HG, Han L. Transitions Between Frailty States Among Community-Living Older Persons. JAMA Internal Medicine 2006, 166: 418-423. PMID: 16505261, DOI: 10.1001/archinte.166.4.418.Peer-Reviewed Original ResearchConceptsFrailty stateOlder personsCommunity-living older personsCommunity-living personsLow physical activitySlow walking speedFrailty transitionsMuscle weaknessProspective studyGreater frailtyNatural courseLess frailtyPhysical activityDaily livingFrailtyWalking speedsWeight lossNonfrailMonthsPersonsParticipantsPrefrailCriteriaPrevention
2020
Cognitive frailty in relation to adverse health outcomes independent of multimorbidity in Chinese older adults
Liu Z, Chen C, Park J, Wu C, Xue Q, Agogo G, Han L, Wu Z. Cognitive frailty in relation to adverse health outcomes independent of multimorbidity in Chinese older adults. Innovation In Aging 2020, 4: 908-909. PMCID: PMC7741254, DOI: 10.1093/geroni/igaa057.3342.Peer-Reviewed Original ResearchChinese older adultsAdverse health outcomesCognitive frailtyHealth outcomesInstrumental ADLOlder adultsPhysical frailtyCognitive impairmentInternational Consensus GroupRetirement Longitudinal StudyPhysical frailty assessmentFrailty assessmentIADL disabilitySecondary preventionDaily livingHigh riskMobility disabilityMultimorbidityConsensus groupFrailtyChina HealthNormal cognitionBaseline cognitionHealthy agingDeathCognitive frailty in relation to adverse health outcomes independent of multimorbidity: results from the China health and retirement longitudinal study
Chen C, Park J, Wu C, Xue Q, Agogo G, Han L, Hoogendijk EO, Liu Z, Wu Z. Cognitive frailty in relation to adverse health outcomes independent of multimorbidity: results from the China health and retirement longitudinal study. Aging 2020, 12: 23129-23145. PMID: 33221750, PMCID: PMC7746379, DOI: 10.18632/aging.104078.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAge FactorsAgedAged, 80 and overChinaCognitionCognitive AgingCognitive DysfunctionDisability EvaluationFemaleFrail ElderlyFrailtyFunctional StatusHealth SurveysHospitalizationHumansLongitudinal StudiesMaleMiddle AgedMobility LimitationMultimorbidityPrognosisRetirementRisk AssessmentRisk FactorsConceptsCognitive frailtyInstrumental ADLPhysical frailtyHealth outcomesCognitive impairmentAdverse health outcomesRetirement Longitudinal StudyPhysical frailty assessmentChinese older adultsFrailty assessmentIADL disabilitySecondary preventionDaily livingHigh riskMobility disabilityMultimorbidityFrailtyChina HealthNormal cognitionBaseline cognitionHealthy agingOlder adultsDeathBasic activitiesHospitalization
2014
Epidemiology of Restricting Fatigue in Older Adults: The Precipitating Events Project
de Rekeneire N, Leo‐Summers L, Han L, Gill TM. Epidemiology of Restricting Fatigue in Older Adults: The Precipitating Events Project. Journal Of The American Geriatrics Society 2014, 62: 476-481. PMID: 24512073, PMCID: PMC4103720, DOI: 10.1111/jgs.12685.Peer-Reviewed Original ResearchConceptsCommunity-living older adultsPhysical frailtyOlder adultsCommunity-living older menEpidemiologic Studies Depression ScaleProspective cohort studySlow gait speedOverall incidence ratePrecipitating Events ProjectCohort studyCumulative incidenceMedian durationGait speedIncidence rateDepression ScaleUsual activitiesOlder menFrailtyDepressionMonthsWomenConsecutive monthsAdultsHigh rateRespective counterparts
2011
The Relationship Between Intervening Hospitalizations and Transitions Between Frailty States
Gill TM, Gahbauer EA, Han L, Allore HG. The Relationship Between Intervening Hospitalizations and Transitions Between Frailty States. The Journals Of Gerontology Series A 2011, 66A: 1238-1243. PMID: 21852286, PMCID: PMC3193526, DOI: 10.1093/gerona/glr142.Peer-Reviewed Original ResearchConceptsFrailty stateGreater frailtyLess frailtyFrail stateOlder personsAdjusted hazard ratioCommunity-living personsLow physical activitySlow walking speedProspective longitudinal studyFrailty statusHazard ratioMuscle weaknessHospitalizationPhysical activityNonfrailPrefrailFrailtyWalking speedsMonthsLongitudinal studyFrailAdverse consequencesExposure rateConsistent effect
2010
Trajectories of Disability in the Last Year of Life
Gill TM, Gahbauer EA, Han L, Allore HG. Trajectories of Disability in the Last Year of Life. New England Journal Of Medicine 2010, 362: 1173-1180. PMID: 20357280, PMCID: PMC2877372, DOI: 10.1056/nejmoa0909087.Peer-Reviewed Original ResearchConceptsCourse of disabilityDisability trajectoriesOrgan failureAdvanced dementiaSudden deathOlder personsSevere disabilityCommunity-dwelling older personsTrajectories of disabilityLevel of disabilityCatastrophic disabilityEnd of lifeProgressive disabilityFunctional statusDeath certificatesCommon conditionBaseline assessmentPredominant trajectoriesMonthly interviewsDeathDisabilityLongitudinal studyDementiaFrailtyDecedents