2005
Infection-Induced Marginal Zone B Cell Production of Borrelia hermsii-Specific Antibody Is Impaired in the Absence of CD1d
Belperron AA, Dailey CM, Bockenstedt LK. Infection-Induced Marginal Zone B Cell Production of Borrelia hermsii-Specific Antibody Is Impaired in the Absence of CD1d. The Journal Of Immunology 2005, 174: 5681-5686. PMID: 15843569, DOI: 10.4049/jimmunol.174.9.5681.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialAntibody SpecificityAntigens, CD1Antigens, CD1dB-Lymphocyte SubsetsBorreliaBorrelia InfectionsDNA, BacterialGerminal CenterImmune SeraImmunity, InnateImmunization, PassiveImmunoglobulin MLymphocyte ActivationLymphocyte DepletionMiceMice, Inbred C57BLMice, KnockoutConceptsMZB cellsActivation markersPathogen burdenMouse serumAbsence of CD1dBlood-borne AgsCD1d-deficient micePathogen-specific IgMActivation marker expressionMarginal zone B cellsT cell helpImmune mouse serumWild-type miceCritical host defenseB cell productionB. hermsiiCD1d expressionSerum levelsCell helpPassive transferSpirochete burdenAb productionSpirochete Borrelia burgdorferiB cellsCell activation
2000
Cutting Edge: CD1d Deficiency Impairs Murine Host Defense Against the Spirochete, Borrelia burgdorferi
Kumar H, Belperron A, Barthold S, Bockenstedt L. Cutting Edge: CD1d Deficiency Impairs Murine Host Defense Against the Spirochete, Borrelia burgdorferi. The Journal Of Immunology 2000, 165: 4797-4801. PMID: 11046002, DOI: 10.4049/jimmunol.165.9.4797.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialAntigens, BacterialAntigens, CD1Antigens, CD1dAntigens, SurfaceBacterial Outer Membrane ProteinsBacterial VaccinesBorrelia burgdorferi GroupDNA, BacterialGenetic Predisposition to DiseaseImmunity, InnateImmunoglobulin GLipoproteinsLyme DiseaseLyme Disease VaccinesMiceMice, Inbred C3HMice, Inbred C57BLMice, KnockoutUrinary BladderConceptsLipid AgsHost defenseCD1d-deficient miceDisease-susceptible miceMurine host defenseRole of CD1dImpair host resistanceBorrelia burgdorferiSusceptible mouse strainsControl miceT cellsCD1 moleculesSpirochete DNADisease profileMouse strainsMiceLyme disease spirocheteInfectionSpirochetesBurgdorferiHost resistancePathogensArthritisCD1dEnhanced production