The impact of nanoparticle ligand density on dendritic-cell targeted vaccines
Bandyopadhyay A, Fine RL, Demento S, Bockenstedt LK, Fahmy TM. The impact of nanoparticle ligand density on dendritic-cell targeted vaccines. Biomaterials 2011, 32: 3094-3105. PMID: 21262534, PMCID: PMC4570971, DOI: 10.1016/j.biomaterials.2010.12.054.Peer-Reviewed Original ResearchConceptsIL-10 responsesDEC-205 receptorIL-10Cytokine responsesT cellsSubsequent T cell responsesBlockade of CD36T cell responsesAntigen delivery systemDifferential cytokine responsesScavenger receptor CD36Vaccine delivery systemDC expressionVaccine efficacyDC functionDC productionReceptor CD36Cell responsesDelivery systemOVA nanoparticlesDelivery of therapeuticsCD36AntigenReceptorsSimilar pattern