2005
Infection-Induced Marginal Zone B Cell Production of Borrelia hermsii-Specific Antibody Is Impaired in the Absence of CD1d
Belperron AA, Dailey CM, Bockenstedt LK. Infection-Induced Marginal Zone B Cell Production of Borrelia hermsii-Specific Antibody Is Impaired in the Absence of CD1d. The Journal Of Immunology 2005, 174: 5681-5686. PMID: 15843569, DOI: 10.4049/jimmunol.174.9.5681.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialAntibody SpecificityAntigens, CD1Antigens, CD1dB-Lymphocyte SubsetsBorreliaBorrelia InfectionsDNA, BacterialGerminal CenterImmune SeraImmunity, InnateImmunization, PassiveImmunoglobulin MLymphocyte ActivationLymphocyte DepletionMiceMice, Inbred C57BLMice, KnockoutConceptsMZB cellsActivation markersPathogen burdenMouse serumAbsence of CD1dBlood-borne AgsCD1d-deficient micePathogen-specific IgMActivation marker expressionMarginal zone B cellsT cell helpImmune mouse serumWild-type miceCritical host defenseB cell productionB. hermsiiCD1d expressionSerum levelsCell helpPassive transferSpirochete burdenAb productionSpirochete Borrelia burgdorferiB cellsCell activation
1987
The Activation of T Lymphocytes
Bockenstedt L, Goldsmith M, Koretzky G, Weiss A. The Activation of T Lymphocytes. Rheumatic Disease Clinics Of North America 1987, 13: 411-430. PMID: 2963355, DOI: 10.1016/s0889-857x(21)00926-1.Peer-Reviewed Original ResearchConceptsSignal transductionSecond messengerCD3/Ti complexSpecific cell surface receptorsCD3/TiIntracellular second messengerCell surface receptorsCellular genesActivation of PKCCell surface moleculesCellular responsesInteraction of ligandsBiochemical studiesCell surfaceSurface receptorsIntracellular eventsT cell activationPI metabolismAntigen-induced activationTransductionSurface moleculesMessengerCell activationComplex resultsActivation