2019
Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy
Atzmony L, Lim YH, Hamilton C, Leventhal JS, Wagner A, Paller AS, Choate KA. Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy. Journal Of The American Academy Of Dermatology 2019, 82: 123-131. PMID: 31449901, PMCID: PMC7039698, DOI: 10.1016/j.jaad.2019.08.043.Peer-Reviewed Original ResearchConceptsPorokeratosis lesionsPorokeratosis palmaris et plantaris disseminataPathogenesis-directed therapyTreatment of porokeratosisWeeks of therapyInitiation of therapyPathway gene mutationsDisseminated superficial actinic porokeratosisPathogenesis-based therapiesCase series designSuperficial actinic porokeratosisAdverse eventsTopical therapyTherapeutic optionsComplete clearanceLinear porokeratosisPatientsActinic porokeratosisTherapyPorokeratosisLesionsGene mutationsModerate improvementLovastatinToxic metabolites
2015
Treatments for Cutaneous Lichen Planus: A Systematic Review and Meta-Analysis
Atzmony L, Reiter O, Hodak E, Gdalevich M, Mimouni D. Treatments for Cutaneous Lichen Planus: A Systematic Review and Meta-Analysis. American Journal Of Clinical Dermatology 2015, 17: 11-22. PMID: 26507510, DOI: 10.1007/s40257-015-0160-6.Peer-Reviewed Original ResearchMeSH KeywordsAcitretinAdministration, CutaneousAntifungal AgentsAnti-Inflammatory Agents, Non-SteroidalCalcitriolDermatologic AgentsEnoxaparinFemaleFibrinolytic AgentsFicusinGlucocorticoidsGriseofulvinHumansKeratolytic AgentsLichen PlanusMaleNon-Randomized Controlled Trials as TopicPhotochemotherapyPhotosensitizing AgentsPUVA TherapyRandomized Controlled Trials as TopicSulfasalazineTreatment OutcomeConceptsNarrow-band ultraviolet B radiationPsoralen plus ultraviolet A photochemotherapyLichen planusControlled trialsRandomized controlled trialsTreatment modalitiesCourse of oral metronidazoleNonrandomized case-control studyWithdrawals due to adverse eventsResponse rateUltraviolet A photochemotherapyComplete response rateLow-dose prednisoloneCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsChronic relapsing courseEffective treatment optionReduction of itchingOverall response rateRegister of Controlled TrialsAdverse event ratesCutaneous lichen planusCase-control studySystematic reviewCochrane Central Register