2020
Retinal Inputs to the Thalamus Are Selectively Gated by Arousal
Liang L, Fratzl A, Reggiani JDS, El Mansour O, Chen C, Andermann ML. Retinal Inputs to the Thalamus Are Selectively Gated by Arousal. Current Biology 2020, 30: 3923-3934.e9. PMID: 32795442, PMCID: PMC7665906, DOI: 10.1016/j.cub.2020.07.065.Peer-Reviewed Original ResearchConceptsVisual thalamusVisual responsesMajority of boutonsTwo-photon calciumCentral visual processingArousal stateIntermediate spatial frequenciesEnhancement of responsesAxonal boutonsRetinal axonsRetinal inputDifferent pupil sizesVisual pathwayThalamusBoutonsMouse thalamusVisual processingMagnitude of responseVisual information channelsDistinct subsetsEarly stagesPupil sizeNeural activityDifferential modulationBehavioral states
2018
A Fine-Scale Functional Logic to Convergence from Retina to Thalamus
Liang L, Fratzl A, Goldey G, Ramesh RN, Sugden AU, Morgan JL, Chen C, Andermann ML. A Fine-Scale Functional Logic to Convergence from Retina to Thalamus. Cell 2018, 173: 1343-1355.e24. PMID: 29856953, PMCID: PMC6003778, DOI: 10.1016/j.cell.2018.04.041.Peer-Reviewed Original ResearchConceptsAxonal boutonsRetinal ganglion cellsTwo-photon calciumImage-forming visionClusters of boutonsVisual thalamusGanglion cellsRetinal axonsBouton clustersThalamusMouse thalamusIndividual axonsDifferent axonsFeature selectivityBoutonsFine-scale organizationAxonsDendritic domainsUltrastructural analysisRetina
2013
GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons
Liang L, Li Y, Potter CJ, Yizhar O, Deisseroth K, Tsien RW, Luo L. GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons. Neuron 2013, 79: 917-931. PMID: 24012005, PMCID: PMC3838762, DOI: 10.1016/j.neuron.2013.06.014.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainDrosophilaGABAergic NeuronsNeural InhibitionNeuropilOlfactory PathwaysOlfactory Receptor NeuronsPheromonesPresynaptic TerminalsSmellConceptsLateral horn neuronsInhibitory projection neuronsInnate olfactory behaviorsInhibitory tonePresynaptic inhibitionDrosophila olfactory systemHigher-order neuronsProjection neuronsAxon terminalsAntennal lobe glomeruliLateral hornConnection specificityDetectable suppressionOlfactory inputOdor responsesNeuronsOlfactory informationOlfactory systemHigher centersParallel inhibitionDifferential effectsDownstream circuitsInhibition motifCircuit motifsInhibition