2008
Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita
Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. Journal Of Dermatological Science 2008, 51: 151-157. PMID: 18495438, PMCID: PMC2587483, DOI: 10.1016/j.jdermsci.2008.04.003.Peer-Reviewed Original ResearchConceptsPachyonychia congenitaQuantitative RT-PCRRT-PCRReal-time RT-PCRQuantitative real-time RT-PCRClinical efficacyGenetic skin disordersClinical trialsCandidate siRNASkin disordersRNA interferenceNovel therapeuticsPotent inhibitionTherapeutic siRNAsClinical applicationDisordersGenetic disordersPhysiciansCongenitaMutant allelesSiRNAHuman diseasesKeratin disordersPatientsDisease
1988
Local and Systemic Implications of Thymidine Catabolism by Human Keratinocytesa
SCHWARTZ P, REUVENI H, MILSTONE L. Local and Systemic Implications of Thymidine Catabolism by Human Keratinocytesa. Annals Of The New York Academy Of Sciences 1988, 548: 115-124. PMID: 2470288, DOI: 10.1111/j.1749-6632.1988.tb18798.x.Chapters
1986
Prescribing Retinoids: The Art and the Science
Milstone L. Prescribing Retinoids: The Art and the Science. JAMA Dermatology 1986, 122: 761-763. DOI: 10.1001/archderm.1986.01660190039011.Commentaries, Editorials and LettersDisorders of keratinizationNodulocystic acneFurther clinical experienceCourse of therapyAcneiform eruptionClinical efficacyGenitourinary tractEffective therapyChronic diseasesEpithelial tumorsEffective treatmentClinical experienceVersatile therapeutic agentsVitamin ASynthetic retinoidsAutosomal recessive ichthyosisTherapeutic agentsBeneficial effectsAcneRetinoidsBiochemical effectsRecessive ichthyosisIsotretinoinCareful observationTherapy