1999
Cell Type‐Specific Expression of the Kv3.1 Gene Is Mediated by a Negative Element in the 5′ Untranslated Region of the Kv3.1 Promoter
Gan L, Hahn S, Kaczmarek L. Cell Type‐Specific Expression of the Kv3.1 Gene Is Mediated by a Negative Element in the 5′ Untranslated Region of the Kv3.1 Promoter. Journal Of Neurochemistry 1999, 73: 1350-1362. PMID: 10501178, DOI: 10.1046/j.1471-4159.1999.0731350.x.Peer-Reviewed Original ResearchMeSH Keywords3T3 Cells5' Untranslated RegionsAnimalsBase SequenceBeta-GalactosidaseBrainCell LineCHO CellsCloning, MolecularCricetinaeGene Expression RegulationGliomaHumansMiceMice, TransgenicMolecular Sequence DataNeuropeptidesOrgan SpecificityPC12 CellsPotassium ChannelsPotassium Channels, Voltage-GatedPromoter Regions, GeneticRatsRecombinant Fusion ProteinsRegulatory Sequences, Nucleic AcidRNA, MessengerShaw Potassium ChannelsTranscription, GeneticTransfectionConceptsType-specific expressionUntranslated regionCell type-specific enhancersCell type-specific expressionCell linesTissue-specific expressionThymidine kinase promoterCell-type specificityTransient transfection assaysKv3.1 potassium channel genePotassium channel genesKv3.1 geneDifferent tissue originsRegulatory fragmentDeletion analysisRegulatory regionsTranscriptional mechanismsTransgenic miceTransfection assaysKinase promoterFunctional analysisChannel genesType specificityPromoterGenes
1998
When, where, and how much? Expression of the Kv3.1 potassium channel in high‐frequency firing neurons
Gan L, Kaczmarek L. When, where, and how much? Expression of the Kv3.1 potassium channel in high‐frequency firing neurons. Developmental Neurobiology 1998, 37: 69-79. PMID: 9777733, DOI: 10.1002/(sici)1097-4695(199810)37:1<69::aid-neu6>3.0.co;2-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAuditory brain stem neuronsVoltage-dependent potassium currentsBrain stem neuronsHigh-frequency firing neuronsKv3.1 potassium channelStem neuronsKv3.1 potassium channel geneLong-term regulationSynaptic inputsPotassium currentPotassium channel genesNeuronsPotassium channelsKv3.1 geneKv3.1 subunitsFiring neuronsHigh frequencyChannel genesCurrent knowledgeChannels altersTranscriptional mechanismsCell-type specificityExpressionGene transcriptionExtrinsic factors