Role of KCNQ potassium channels in stress-induced deficit of working memory
Arnsten AFT, Jin LE, Gamo NJ, Ramos B, Paspalas CD, Morozov YM, Kata A, Bamford NS, Yeckel MF, Kaczmarek LK, El-Hassar L. Role of KCNQ potassium channels in stress-induced deficit of working memory. Neurobiology Of Stress 2019, 11: 100187. PMID: 31832507, PMCID: PMC6889760, DOI: 10.1016/j.ynstr.2019.100187.Peer-Reviewed Original ResearchStress-induced deficitsKCNQ potassium channelsKCNQ blockersPrefrontal cortexNeuronal firingLayers II/IIIRat medial prefrontal cortexStress exposurePotassium channelsRat medial PFCMedial PFCChronic stress exposurePatch-clamp recordingsPyramidal cell firingMedial prefrontal cortexSystemic administrationPyramidal cellsAged ratsLow dosePFC dysfunctionHigh dosesKCNQ channelsLow dosesCell firingCognitive function