2021
High Hopes for Very Preterm Infants in Neonatal Intensive Care Units in China
Soma G, Chen L. High Hopes for Very Preterm Infants in Neonatal Intensive Care Units in China. JAMA Network Open 2021, 4: e2113649. PMID: 34137833, DOI: 10.1001/jamanetworkopen.2021.13649.Peer-Reviewed Original Research
2018
Reasons for parental withdrawal of care in a pediatric intensive care unit in China
Ho K, Wang X, Chen L. Reasons for parental withdrawal of care in a pediatric intensive care unit in China. PLOS ONE 2018, 13: e0199419. PMID: 30044777, PMCID: PMC6059386, DOI: 10.1371/journal.pone.0199419.Peer-Reviewed Original ResearchConceptsPediatric intensive care unitIntensive care unitClinical improvementCare unitDisease severityNon-withdrawal groupMean hospital chargesDay of deathICU stayHospital stayHospital chargesWithdrawal groupMedical costsMedical carePatientsCareSubstantial proportionAdmissionStaySubstantial numberSeverityLower disease severityFinancial hardshipLarge proportionDays
2012
Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children
Faustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, Card ME, Northrup V, Baker KE, Goodman TR, Chen L, Silva CT. Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children. The Journal Of Pediatrics 2012, 162: 387-391. PMID: 22883418, PMCID: PMC3575007, DOI: 10.1016/j.jpeds.2012.06.059.Peer-Reviewed Original ResearchConceptsCVC-related deep venous thrombosisDeep venous thrombosisCentral venous cathetersIntensive care unitAcute complicationsIll childrenVenous cathetersVenous thrombosisCare unitPediatric intensive care unitProspective cohort studyChronic complicationsHospital lengthCohort studyPatient demographicsPulmonary embolismCompression ultrasonographyMechanical ventilationHigher oddsCurrent incidenceColor DopplerComplicationsCVC characteristicsLarger studyThrombosisUltrasound Evaluation of Skull Fractures in Children
Riera A, Chen L. Ultrasound Evaluation of Skull Fractures in Children. Pediatric Emergency Care 2012, 28: 420-425. PMID: 22531195, DOI: 10.1097/pec.0b013e318252da3b.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolDiagnosis, DifferentialFeasibility StudiesFemaleFollow-Up StudiesHumansInfantInfant, NewbornMalePilot ProjectsPoint-of-Care SystemsPredictive Value of TestsProspective StudiesROC CurveSkull FracturesTomography, X-Ray ComputedTrauma Severity IndicesUltrasonographyConceptsAcute closed head injuryClosed head injurySkull fractureBedside ultrasoundPediatric emergency medicineCT scanUrban tertiary care children's hospitalPredictive valueTertiary care children's hospitalTest characteristicsUnnecessary CT scansClinical decision rulePediatric emergency departmentEmergency medicineComputed tomography scanNegative predictive valuePositive predictive valueMonths of trainingMedian ageChildren's HospitalUltrasound evaluationEmergency departmentHead injuryBedside ultrasonographyTomography scanDiagnosis of Intussusception by Physician Novice Sonographers in the Emergency Department
Riera A, Hsiao AL, Langhan ML, Goodman TR, Chen L. Diagnosis of Intussusception by Physician Novice Sonographers in the Emergency Department. Annals Of Emergency Medicine 2012, 60: 264-268. PMID: 22424652, PMCID: PMC3431911, DOI: 10.1016/j.annemergmed.2012.02.007.Peer-Reviewed Original ResearchConceptsPediatric emergency physiciansIleocolic intussusceptionEmergency physiciansUltrasonographic resultsUrban tertiary care children's hospitalPredictive valueBedside emergency department ultrasonographyTertiary care children's hospitalEmergency department ultrasonographyDiagnosis of intussusceptionProspective convenience sample studyLikelihood ratioNegative predictive valuePositive predictive valueConvenience sample studyBowel ultrasonographyMedian agePediatric EDChildren's HospitalUltrasonographic studyEmergency departmentObservational studyPhysician sonographersBedside studiesIntussusception
2010
Use of Bedside Ultrasound to Assess Degree of Dehydration in Children With Gastroenteritis
Chen L, Hsiao A, Langhan M, Riera A, Santucci KA. Use of Bedside Ultrasound to Assess Degree of Dehydration in Children With Gastroenteritis. Academic Emergency Medicine 2010, 17: 1042-1047. PMID: 21040104, PMCID: PMC3058669, DOI: 10.1111/j.1553-2712.2010.00873.x.Peer-Reviewed Original ResearchMeSH KeywordsAortaChildChild, PreschoolCohort StudiesDehydrationDiarrheaEmergency Service, HospitalFemaleFluid TherapyGastroenteritisHemodynamicsHumansInfantInfusions, IntravenousLinear ModelsMaleObserver VariationPilot ProjectsPoint-of-Care SystemsProspective StudiesReproducibility of ResultsSeverity of Illness IndexUltrasonography, DopplerVena Cava, InferiorConceptsInferior vena cavaIVC/Ao ratioPediatric emergency departmentAo diametersAcute gastroenteritisAo ratioBedside ultrasound measurementAcute weight lossProspective observational studyResolution of symptomsAorta diameter ratioAcute care settingInterrater reliabilityPairs of investigatorsPearson correlation coefficientSignificant dehydrationGood interrater reliabilityEmergency departmentIntravascular volumeBedside USVena cavaBedside ultrasoundObservational studyCare settingsProspective identification
2007
Use of Ultrasound Measurement of the Inferior Vena Cava Diameter as an Objective Tool in the Assessment of Children with Clinical Dehydration
Chen L, Kim Y, Santucci KA. Use of Ultrasound Measurement of the Inferior Vena Cava Diameter as an Objective Tool in the Assessment of Children with Clinical Dehydration. Academic Emergency Medicine 2007, 14: 841-845. PMID: 17898246, DOI: 10.1197/j.aem.2007.06.040.Peer-Reviewed Original ResearchConceptsIVC/Ao ratioInferior vena cavaAo ratioInferior vena cava diameterUrban pediatric emergency departmentMean differenceUS measurementsProspective observational studyVena cava diameterPediatric emergency departmentWeight-matched controlsYears of ageIntravenous rehydrationClinical evidenceClinical dehydrationEmergency departmentVena cavaAssessment of childrenObservational studyDehydrated childrenUltrasonography measurementsUltrasound measurementsRank testObjective toolChildren
2006
Incidence and Predictors of Serious Bacterial Infections Among 57- to 180-Day-Old Infants
Hsiao AL, Chen L, Baker MD. Incidence and Predictors of Serious Bacterial Infections Among 57- to 180-Day-Old Infants. Pediatrics 2006, 117: 1695-1701. PMID: 16651326, DOI: 10.1542/peds.2005-1673.Peer-Reviewed Original ResearchConceptsSerious bacterial illnessWhite blood cell countDirect fluorescent antibodyBlood cell countPositive direct fluorescent antibodyCell countOlder infantsEtiology of feverHeight of feverOlder febrile infantsSerious bacterial infectionsRespiratory syncytial virusMonths of ageFebrile infantsPneumococcal diseaseBacterial meningitisVaccine eraRespiratory virusesProspective studySyncytial virusLumbar punctureUrine testsBacterial illnessNasal swabsFever
2005
Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children
Chen L, Hsiao AL, Moore CL, Dziura JD, Santucci KA. Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children. Pediatrics 2005, 115: 108-111. PMID: 15629989, DOI: 10.1542/peds.2004-0738.Peer-Reviewed Original ResearchConceptsPediatric emergency medicine physiciansAmount of urineUrethral catheterizationEmergency medicine physiciansBedside ultrasoundSufficient urineMedicine physiciansUrban pediatric emergency departmentIntervention phasePediatric emergency departmentPediatric emergency physiciansSuccess rateObservation phaseSimple noninvasive procedureSubsequent ultrasoundBladder ultrasoundFirst catheterizationUnsuccessful proceduresUrine cultureEmergency departmentIntervention periodInvasive testingEmergency physiciansCatheterizationUncomfortable procedure