2022
Systematic Review of Sex Differences in Ischemic Strokes Among Young Adults: Are Young Women Disproportionately at Risk?
Leppert M, Burke J, Lisabeth L, Madsen T, Kleindorfer D, Sillau S, Schwamm L, Daugherty S, Bradley C, Ho P, Poisson S. Systematic Review of Sex Differences in Ischemic Strokes Among Young Adults: Are Young Women Disproportionately at Risk? Stroke 2022, 53: 319-327. PMID: 35073188, PMCID: PMC8852306, DOI: 10.1161/strokeaha.121.037117.Peer-Reviewed Original ResearchConceptsIschemic strokeIncidence rate ratiosYoung adultsStroke incidenceSex-specific incidence rate ratiosSystematic reviewAge groupsSex differencesYoung womenMore womenRate ratioAdults 35Incidence rateStroke typeHigh riskAge adjustmentStrokeSignificant sex differencesRelevant articlesMore menWomenNonsignificant sex differencesAdultsRecent evidenceMen
2017
Early transition to comfort measures only in acute stroke patients
Prabhakaran S, Cox M, Lytle B, Schulte P, Xian Y, Zahuranec D, Smith E, Reeves M, Fonarow G, Schwamm L. Early transition to comfort measures only in acute stroke patients. Neurology Clinical Practice 2017, 7: 194-204. PMID: 28680764, PMCID: PMC5490382, DOI: 10.1212/cpj.0000000000000358.Peer-Reviewed Original ResearchIntracerebral hemorrhageIschemic strokeStroke patientsHospital characteristicsComfort measuresCMO orderGuidelines-Stroke registryHospital days 0Acute stroke patientsMultivariable logistic regressionRisk-adjusted mortalityLife-sustaining interventionsLife-sustaining treatmentAcute strokeNonambulatory statusHospital factorsMultivariable analysisStudy criteriaFemale sexStroke typeWhite racePatientsDay 0Older ageLogistic regression
2016
Chapter 16 Imaging acute ischemic stroke
González R, Schwamm L. Chapter 16 Imaging acute ischemic stroke. Handbook Of Clinical Neurology 2016, 135: 293-315. PMID: 27432672, DOI: 10.1016/b978-0-444-53485-9.00016-7.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIschemic strokeCurrent evidence-based approachesSevere stroke syndromesIschemic stroke patientsPresence of hemorrhageMassachusetts General HospitalEvidence-based approachStroke syndromeAcute strokeAnterior circulationMajor strokeMore patientsArterial occlusionStroke patientsBrain parenchymaGeneral HospitalStroke typeCommon causeClinical valueComputed tomographyModern neuroimagingMagnetic resonance imaging methodLarge arteriesStroke evolution
2015
An International Standard Set of Patient-Centered Outcome Measures After Stroke
Salinas J, Sprinkhuizen S, Ackerson T, Bernhardt J, Davie C, George M, Gething S, Kelly A, Lindsay P, Liu L, Martins S, Morgan L, Norrving B, Ribbers G, Silver F, Smith E, Williams L, Schwamm L. An International Standard Set of Patient-Centered Outcome Measures After Stroke. Stroke 2015, 47: 180-186. PMID: 26604251, PMCID: PMC4689178, DOI: 10.1161/strokeaha.115.010898.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesOutcome measuresInternational standard setTransient ischemic attackHealth-related qualityCare-related factorsStroke Outcome MeasureSystemic risk factorsDifferent care settingsPreferred outcome measureRisk-adjustment variablesValue-based health careInternational expert panelIschemic attackAcute complicationsIschemic strokePatient demographicsStroke outcomeStroke RegisterIntracerebral hemorrhageStroke careStroke managementRisk factorsStroke typeCare settings
2013
A Risk Score for In‐Hospital Death in Patients Admitted With Ischemic or Hemorrhagic Stroke
Smith E, Shobha N, Dai D, Olson D, Reeves M, Saver J, Hernandez A, Peterson E, Fonarow G, Schwamm L. A Risk Score for In‐Hospital Death in Patients Admitted With Ischemic or Hemorrhagic Stroke. Journal Of The American Heart Association 2013, 2: e005207. PMID: 23525444, PMCID: PMC3603253, DOI: 10.1161/jaha.112.005207.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaCerebral HemorrhageChi-Square DistributionDecision Support TechniquesFemaleHospital MortalityHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsRegistriesReproducibility of ResultsRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeSubarachnoid HemorrhageUnited StatesConceptsStroke typeIschemic strokeIntracerebral hemorrhageRisk scoreGuidelines-Stroke databaseHealth Stroke ScaleIn-Hospital DeathRisk of deathHospital mortalityHospital deathStroke ScaleStroke admissionsIndependent predictorsHemorrhagic strokeStroke patientsC-statisticSingle risk scoreOverall populationLogistic regressionPatientsValidation sampleMortalityDeathPoint scorePrediction score
2012
Standardizing the Structure of Stroke Clinical and Epidemiologic Research Data
Saver J, Warach S, Janis S, Odenkirchen J, Becker K, Benavente O, Broderick J, Dromerick A, Duncan P, Elkind M, Johnston K, Kidwell C, Meschia J, Schwamm L. Standardizing the Structure of Stroke Clinical and Epidemiologic Research Data. Stroke 2012, 43: 967-973. PMID: 22308239, PMCID: PMC3493110, DOI: 10.1161/strokeaha.111.634352.Peer-Reviewed Original ResearchConceptsCommon data elementsNeurological disordersStroke Common Data ElementsLong-term therapyClinical practice guidelinesNational InstituteCase report formsPrior health statusPatient-oriented researchAcute therapyHospital courseStroke presentationCerebrovascular diseaseMedical historyNational registryClinical trialsStroke typePractice guidelinesHealth statusEnd pointVital signsClinical researchReport formsData elementsTherapy