Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty
Del Toro-Pagán NM, Dai F, Banack T, Berlin J, Makadia SA, Rubin LE, Zhou B, Huynh P, Li J. Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty. Journal Of Pain Research 2022, 15: 2537-2546. PMID: 36061486, PMCID: PMC9432382, DOI: 10.2147/jpr.s378243.Peer-Reviewed Original ResearchWhite blood cell countTotal knee arthroplastyActive pain scoresCumulative opioid consumptionOpioid consumptionPostoperative opioid consumptionMethylprednisolone acetateMPA groupPain scoresPostoperative dayNerve blockDEX groupKnee arthroplastySingle-injection nerve blocksConsecutive TKA patientsDaily opioid consumptionPosterior knee (IPACK) blockLocal anesthetic adjuvantBlood cell countLength of stayHigher restKnee blockHospital stayTKA patientsSecondary outcomes