Featured Publications
Unicompartmental Knee Arthroplasty in Octogenarians: A National Database Analysis Including Over 700 Octogenarians
Moore HG, Schneble CA, Kahan JB, Grauer JN, Rubin LE. Unicompartmental Knee Arthroplasty in Octogenarians: A National Database Analysis Including Over 700 Octogenarians. Arthroplasty Today 2022, 15: 55-60. PMID: 35399988, PMCID: PMC8991237, DOI: 10.1016/j.artd.2022.02.009.Peer-Reviewed Original ResearchUnicompartmental knee arthroplastyAdverse eventsMedical comorbiditiesKnee arthroplastyNational Surgical Quality Improvement Program databaseLarge national surgical databaseQuality Improvement Program databaseHigher comorbidity burdenMinor adverse eventsPostoperative adverse eventsSerious adverse eventsImprovement Program databaseProlonged hospital stayUrinary tract infectionDay of surgeryNational database analysisNational surgical databaseShort-term mortalityMultivariate regression analysisComorbidity burdenOctogenarian cohortHospital lengthHospital stayNonhome dischargeSelect patientsCenters for Medicare & Medicaid Services' 2018 Removal of Total Knee Arthroplasty From the Inpatient-only List Led to Broad Changes in Hospital Length of Stays
Rankin KA, Freedman IG, Rubin LE, Grauer JN. Centers for Medicare & Medicaid Services' 2018 Removal of Total Knee Arthroplasty From the Inpatient-only List Led to Broad Changes in Hospital Length of Stays. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 29: 1061-1067. PMID: 33960970, DOI: 10.5435/jaaos-d-20-01228.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyHospital lengthKnee arthroplastyNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMedicare eligibilityCategorical data comparisonsOverall practice patternsRetrospective cohort studyImprovement Program databaseSame dayRemoval of TKAPearson's chi-squared testChi-squared testMann-Whitney testLOS daysProlonged LOSMost patientsTKA patientsCohort studyMore patientsPractice patternsPatient characterizationProgram databaseActual LOS
2022
Jump in Elective Total Hip and Knee Arthroplasty Numbers at Age 65 Years: Evidence for Moral Hazard?
Rankin KA, Freedman IG, Moore HG, Halperin SJ, Rubin LE, Grauer JN. Jump in Elective Total Hip and Knee Arthroplasty Numbers at Age 65 Years: Evidence for Moral Hazard? JAAOS Global Research And Reviews 2022, 6: e22.00035. PMID: 35315795, PMCID: PMC8942773, DOI: 10.5435/jaaosglobal-d-22-00035.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyAge 65 yearsNational Surgical Quality Improvement Program databaseIncidence of TKAElective total knee arthroplastyQuality Improvement Program databaseLower body mass indexElective total hipPostoperative adverse eventsPreoperative American SocietyImprovement Program databaseLower functional statusBody mass indexNon-Hispanic whitesNumber of proceduresAnesthesiologists classPreoperative characteristicsOlder patientsAdverse eventsTHA patientsMass indexTotal hipFunctional statusKnee arthroplasty
2021
Does dehydration prior to primary total joint arthroplasty increase risk of perioperative complications?
Moore HG, Justen MA, Kirwin DS, Burroughs PJ, Rubin LE, Grauer JN. Does dehydration prior to primary total joint arthroplasty increase risk of perioperative complications? Arthroplasty 2021, 3: 34. PMID: 35236481, PMCID: PMC8796573, DOI: 10.1186/s42836-021-00090-8.Peer-Reviewed Original ResearchPreoperative dehydrationPerioperative complicationsTotal joint arthroplastyTKA patientsTHA patientsJoint arthroplastyNational Surgical Quality Improvement Program databaseElective total joint arthroplastyQuality Improvement Program databasePrimary total joint arthroplastyTotal knee arthroplasty patientsImprovement Program databaseRisk of transfusionShort-term complicationsTHA/TKAKnee arthroplasty patientsMethodsThe 2012Perioperative outcomesBlood transfusionArthroplasty patientsSpecific complicationsTotal hipProgram databaseBackgroundPrior studiesIncrease riskLong-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery.
Kebaish KJ, Galivanche AR, Varthi AG, Ottesen TD, Rubin LE, Grauer JN. Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery. Orthopedics 2021, 44: 172-179. PMID: 34039214, DOI: 10.3928/01477447-20210416-01.Peer-Reviewed Original ResearchConceptsLong-term corticosteroid usePosterior lumbar spine surgeryPosterior lumbar surgeryLumbar spine surgeryPerioperative adverse outcomesCorticosteroid useAdverse eventsLumbar surgerySpine surgeryPropensity matchingAdverse outcomesNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsEffect of immunosuppressionImprovement Program databaseLong-term corticosteroidsSerious adverse eventsBody mass indexMultiple surgical specialtiesAnesthesiologists classComparable patientsPerioperative outcomesSurgical factorsMore patientsUnderweight Patients Are the Greatest Risk Body Mass Index Group for 30-Day Perioperative Adverse Events After Total Shoulder Arthroplasty.
Ottesen TD, Hsiang WR, Malpani R, Nicholson AD, Varthi AG, Rubin LE, Grauer JN. Underweight Patients Are the Greatest Risk Body Mass Index Group for 30-Day Perioperative Adverse Events After Total Shoulder Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 29: e132-e142. PMID: 32568997, DOI: 10.5435/jaaos-d-20-00049.Peer-Reviewed Original ResearchConceptsBody mass indexPerioperative adverse eventsTotal shoulder arthroplastyNormal weight patientsAdverse eventsTSA patientsBMI categoriesUnderweight patientsShoulder arthroplastyNational Surgical Quality Improvement Program databaseElective total shoulder arthroplastyOverweight/obese categoriesRisk-adjusted multivariate regressionsQuality Improvement Program databaseElevated body mass indexBody mass index groupsLower body mass indexPrimary total shoulder arthroplastyNormal BMI patientsComplications of patientsSerious adverse eventsImprovement Program databaseNormal-weight subjectsBMI patientsFragile cohort
2020
Coagulopathies Are a Risk Factor for Adverse Events Following Total Hip and Total Knee Arthroplasty.
Malpani R, Mclynn RP, Bovonratwet P, Bagi PS, Yurter A, Mercier MR, Rubin LE, Grauer JN. Coagulopathies Are a Risk Factor for Adverse Events Following Total Hip and Total Knee Arthroplasty. Orthopedics 2020, 43: 233-238. PMID: 32674174, DOI: 10.3928/01477447-20200624-02.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overArthroplasty, Replacement, HipArthroplasty, Replacement, KneeBlood Coagulation DisordersDatabases, FactualFemaleHumansMaleMiddle AgedMultivariate AnalysisOutcome Assessment, Health CarePatient ReadmissionPostoperative ComplicationsRetrospective StudiesRisk FactorsYoung AdultConceptsHigher international normalized ratioInternational normalized ratioMajor adverse eventsTotal hip arthroplastyPartial thromboplastin timeHigher partial thromboplastin timeMinor adverse eventsAdverse eventsLow plateletsHematological conditionsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseTotal knee arthroplasty (TKA) populationQuality Improvement Program databasePrimary total hip arthroplastyDependent functional statusImprovement Program databasePostsurgical adverse eventsTotal knee arthroplastyMultiple adverse eventsPreoperative coagulopathyTHA cohortTKA groupTKA patientsHospital readmissionPostoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications.
Galivanche AR, Kebaish KJ, Adrados M, Ottesen TD, Varthi AG, Rubin LE, Grauer JN. Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 28: 342-351. PMID: 31567615, DOI: 10.5435/jaaos-d-19-00104.Peer-Reviewed Original ResearchConceptsPostoperative pressure ulcersHip fracture surgeryPostoperative complicationsPressure ulcersRisk factorsPreoperative comorbiditiesFracture surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseGeriatric hip fracture patientsGeriatric hip fracture surgeryQuality Improvement Program databaseMultivariate regressionNSQIP Participant Use FilePreoperative risk factorsHip fracture patientsImprovement Program databaseUrinary tract infectionElevated platelet countInsulin-dependent diabetesParticipant Use FilePressure ulcer developmentQuality Improvement ProgramPostoperative deliriumPostoperative pneumonia
2019
Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities
Ottesen TD, Yurter A, Shultz BN, Galivanche AR, Zogg CK, Bovonratwet P, Rubin LE, Grauer JN. Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities. JAAOS Global Research And Reviews 2019, 3: e086. PMID: 31592508, PMCID: PMC6754213, DOI: 10.5435/jaaosglobal-d-19-00086.Peer-Reviewed Original ResearchHip fracture surgeryDialysis-dependent patientsPerioperative adverse eventsAdverse eventsFracture surgeryDialysis dependenceDialysis patientsHip fractureGreater oddsNational Surgical Quality Improvement Program databaseGeriatric hip fracture surgeryRisk-adjusted logistic regressionQuality Improvement Program databaseInstitutional cohort studyNational patient populationPreoperative dialysis dependenceMinor adverse eventsHip fracture careImprovement Program databaseMajor adverse eventsDemographic factorsUnplanned readmissionCohort studyPerioperative periodPostoperative day
2018
Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery
Ottesen TD, McLynn RP, Zogg CK, Shultz BN, Ondeck NT, Bovonratwet P, Bellamkonda KS, Rubin LE, Grauer JN. Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery. The Spine Journal 2018, 18: 2033-2042. PMID: 30077772, DOI: 10.1016/j.spinee.2018.04.007.Peer-Reviewed Original ResearchConceptsElective spine surgeryNon-dialysis patientsDialysis-dependent patientsPerioperative adverse eventsAdverse eventsDialysis patientsSpine surgeryUnplanned readmissionCohort studyPatient demographicsRisk factorsNational Surgical Quality Improvement Program databaseRisk-adjusted multivariate regressionsQuality Improvement Program databaseOperating roomDialysis-independent patientsInstitutional cohort studyMinor adverse eventsRetrospective cohort studyElective spinal surgeryImprovement Program databaseIndependent risk factorMajor adverse eventsPercentage of complicationsAdministrative database studyAseptic revision total hip arthroplasty in the elderly : quantifying the risks for patients over 80 years old.
Bovonratwet P, Malpani R, Ottesen TD, Tyagi V, Ondeck NT, Rubin LE, Grauer JN. Aseptic revision total hip arthroplasty in the elderly : quantifying the risks for patients over 80 years old. The Bone & Joint Journal 2018, 100-B: 143-151. PMID: 29437055, DOI: 10.1302/0301-620x.100b2.bjj-2017-0895.r1.Peer-Reviewed Original ResearchConceptsAseptic revision total hip arthroplastyRevision total hip arthroplastyTotal hip arthroplastySerious adverse eventsAdverse eventsRisk factorsProcedural characteristicsHip arthroplastyNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseIndependent risk factorUrinary tract infectionMultivariate regression analysisAnesthesiologists (ASA) scoreMedical optimizationPerioperative complicationsPerioperative mortalityPostoperative complicationsTract infectionsYounger patientsBlood transfusionGeneral anesthesiaVulnerable patientsBone Joint
2017
Revision Total Knee Arthroplasty in Octogenarians: An Analysis of 957 Cases
Bovonratwet P, Tyagi V, Ottesen TD, Ondeck NT, Rubin LE, Grauer JN. Revision Total Knee Arthroplasty in Octogenarians: An Analysis of 957 Cases. The Journal Of Arthroplasty 2017, 33: 178-184. PMID: 28844628, DOI: 10.1016/j.arth.2017.07.032.Peer-Reviewed Original ResearchConceptsRevision total knee arthroplastyTotal knee arthroplastyBlood transfusionOctogenarian patientsKnee arthroplastyPatient populationNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseLonger lengthYoung populationHigh rateImprovement Program databaseYoung patient populationNumber of octogenariansLarger patient populationYear oldsHospital stayIntraoperative characteristicsPerioperative complicationsPerioperative coursePropensity matchingAdvanced ageProgram databaseOctogenariansStayOutpatient and Inpatient Unicompartmental Knee Arthroplasty Procedures Have Similar Short-Term Complication Profiles
Bovonratwet P, Ondeck NT, Tyagi V, Nelson SJ, Rubin LE, Grauer JN. Outpatient and Inpatient Unicompartmental Knee Arthroplasty Procedures Have Similar Short-Term Complication Profiles. The Journal Of Arthroplasty 2017, 32: 2935-2940. PMID: 28602533, DOI: 10.1016/j.arth.2017.05.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAmbulatory Surgical ProceduresArthroplasty, Replacement, KneeCohort StudiesComorbidityDatabases, FactualFemaleHumansInpatientsLength of StayMaleMiddle AgedOutcome Assessment, Health CareOutpatientsPatient ReadmissionPatient SatisfactionPostoperative ComplicationsPropensity ScoreQuality ImprovementUnited StatesConceptsUnicompartmental knee arthroplastyNational Surgical Quality Improvement Program databaseInpatient Unicompartmental Knee ArthroplastyQuality Improvement Program databaseLength of hospitalImprovement Program databasePerioperative complicationsProgram databaseOutpatient unicompartmental knee arthroplastyShort-term complication profileUnicompartmental knee arthroplasty (UKA) proceduresNational patient populationPerioperative outcome measuresHigh patient satisfactionKnee arthroplasty proceduresPotential confounding factorsInpatient cohortPerioperative outcomesPostdischarge complicationsPatient characteristicsComplication profileOutpatient surgeryPatient populationKnee arthroplastyOutpatient procedure