2009
A Crystallized View of AMPK Activation
Young LH. A Crystallized View of AMPK Activation. Cell Metabolism 2009, 10: 5-6. PMID: 19583947, DOI: 10.1016/j.cmet.2009.06.008.Commentaries, Editorials and LettersConceptsAMPK activationAMPK catalytic subunitKey metabolic regulatorAutoinhibitory sequenceCatalytic subunitKinase domainProtein kinaseMetabolic regulatorStructural interactionsCrystallized viewNovel therapeutic approachesActivationKinaseSubunitsRegulatorEnhanced understandingRecent workSequenceTherapeutic approachesMolecular mechanicsDomain
2005
AMPK – A pivotal rheostat in the control of cardiac metabolism
Miller E, Russell R, Li J, Young L. AMPK – A pivotal rheostat in the control of cardiac metabolism. Drug Discovery Today Disease Mechanisms 2005, 2: 93-100. DOI: 10.1016/j.ddmec.2005.05.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMyocardial stress responseRegulation of AMPKProtein kinaseCentral regulatorStress responseAMPKNon-metabolic actionsCoronary artery diseaseNovel cardioprotective strategiesType 2 diabetesPotential novel approachArtery diseaseCardioprotective strategiesCardiac metabolismMetabolic actionsPossible roleKinaseRheostatRegulatorRegulationMetabolismDiabetesDisease