2000
Hippocampal Volume Reduction in Major Depression
Bremner J, Narayan M, Anderson E, Staib L, Miller H, Charney D. Hippocampal Volume Reduction in Major Depression. American Journal Of Psychiatry 2000, 157: 115-118. PMID: 10618023, DOI: 10.1176/ajp.157.1.115.Peer-Reviewed Original ResearchConceptsSmaller left hippocampal volumeLeft hippocampal volumeHippocampal volumeMajor depressionComparison subjectsHippocampal volume reductionWhole brain volumeMagnetic resonance imagingNondepressed comparison subjectsAlcohol exposureBrain areasBrain volumeResonance imagingPatientsElevated levelsDepressionHippocampusVolume reductionComparison regionBrain sizeSubjectsRemissionGlucocorticoidsFindings
1997
Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report
Bremner J, Randall P, Vermetten E, Staib L, Bronen R, Mazure C, Capelli S, McCarthy G, Innis R, Charney D. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report. Biological Psychiatry 1997, 41: 23-32. PMID: 8988792, PMCID: PMC3229101, DOI: 10.1016/s0006-3223(96)00162-x.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderLeft hippocampal volumeHippocampal volumeChildhood abuseAdult survivorsSmaller left hippocampal volumeAbuse-related posttraumatic stress disorderStress disorderSmaller hippocampal volumesCombat-related posttraumatic stress disorderMagnetic resonance imagingShort-term memoryHealthy subjectsYears of educationAlcohol abuseMagnetic resonance imaging-based measurementsComparison subjectsPTSD patientsImaging-based measurementsResonance imagingPatientsSexual abusePreliminary reportSurvivorsComparison region