Regional myocardial strain analysis via 2D speckle tracking echocardiography: validation with sonomicrometry and correlation with regional blood flow in the presence of graded coronary stenoses and dobutamine stress
Stendahl JC, Parajuli N, Lu A, Boutagy NE, Guerrera N, Alkhalil I, Lin BA, Staib LH, O’Donnell M, Duncan JS, Sinusas AJ. Regional myocardial strain analysis via 2D speckle tracking echocardiography: validation with sonomicrometry and correlation with regional blood flow in the presence of graded coronary stenoses and dobutamine stress. Cardiovascular Ultrasound 2020, 18: 2. PMID: 31941514, PMCID: PMC6964036, DOI: 10.1186/s12947-019-0183-x.Peer-Reviewed Original ResearchConceptsSpeckle tracking echocardiographyLow-dose dobutamine stressPost-systolic indexDobutamine stressCoronary stenosisBlood flow measurementsTracking echocardiographyAnesthetized open-chest dogsCircumferential strainLow-dose dobutamineMid-left anteriorModerate coronary stenosisOpen-chest dogsRegional blood flowAcute canine modelMyocardial strain analysisMicrosphere blood flow measurementsLAD stenosis