MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder
Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Nazeer A, Khan S, Vaccarino LV, Soufer R, Garg PK, Ng CK, Staib LH, Duncan JS, Charney DS. MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder. American Journal Of Psychiatry 2003, 160: 924-932. PMID: 12727697, DOI: 10.1176/appi.ajp.160.5.924.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderChildhood sexual abuseHippocampal volumeEarly childhood sexual abuseHippocampal structureHippocampal functionAbuse-related posttraumatic stress disorderStress disorderSmaller hippocampal volumesPositron emission tomographySexual abuseVerbal declarative memory tasksAnimal studiesBrain areasDeclarative memory taskEmission tomographyPET studiesHippocampal activationWomenEarly stressHippocampusAbused womenDisordersAbuseMagnetic resonance