Anterior Cortical Development During Adolescence in Bipolar Disorder
Najt P, Wang F, Spencer L, Johnston JA, Lippard E, Pittman BP, Lacadie C, Staib LH, Papademetris X, Blumberg HP. Anterior Cortical Development During Adolescence in Bipolar Disorder. Biological Psychiatry 2015, 79: 303-310. PMID: 26033826, PMCID: PMC4595154, DOI: 10.1016/j.biopsych.2015.03.026.Peer-Reviewed Original ResearchConceptsWhite matter expansionBipolar disorderWhite matterAnterior cortexHealthy adolescentsHigh-resolution magnetic resonance imaging (MRI) scansMagnetic resonance imaging (MRI) scansWhite matter increasesResonance imaging scansGray matter decreasesDorsolateral prefrontal cortexMatter expansionHealthy groupImaging scansCortical volumeFrontal cortexNeurodevelopmental abnormalitiesCortical developmentAnterior paralimbicNeurodevelopmental modelLongitudinal neuroimagingPrefrontal cortexCortexLongitudinal studyAdolescents