2015
Human Adult Retinal Pigment Epithelial Stem Cell–Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native TissuePhysiology of Cultured Adult Human RPE
Blenkinsop TA, Saini JS, Maminishkis A, Bharti K, Wan Q, Banzon T, Lotfi M, Davis J, Singh D, Rizzolo LJ, Miller S, Temple S, Stern JH. Human Adult Retinal Pigment Epithelial Stem Cell–Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native TissuePhysiology of Cultured Adult Human RPE. Investigative Ophthalmology & Visual Science 2015, 56: 7085-7099. PMID: 26540654, PMCID: PMC4640474, DOI: 10.1167/iovs.14-16246.Peer-Reviewed Original Research
2008
A Novel Rabbit Model for Studying RPE Transplantation
Cong L, Sun D, Zhang Z, Jiao W, Rizzolo LJ, Peng S. A Novel Rabbit Model for Studying RPE Transplantation. Investigative Ophthalmology & Visual Science 2008, 49: 4115-4125. PMID: 18502985, PMCID: PMC2568003, DOI: 10.1167/iovs.08-1976.Peer-Reviewed Original ResearchConceptsOptical coherence tomographySubretinal spaceIntact blood-retinal barrierRetinal pigment epithelium (RPE) transplantationRabbit RPEBlood-retinal barrierConfocal scanning laserNovel rabbit modelZonula occludens-1CFDA-SEFunctional RPE monolayerTransepithelial electrical resistanceTransplanted RPEFundus photographyConjunctival flapRPE transplantationTransplantation protocolsLabeled cellsRabbit modelCoherence tomographyOccludens-1RPE cellsRPE monolayerPrimary cultures
2000
Two secreted retinal factors regulate different stages of development of the outer blood–retinal barrier
Ban Y, Wilt S, Rizzolo L. Two secreted retinal factors regulate different stages of development of the outer blood–retinal barrier. Brain Research 2000, 119: 259-267. PMID: 10675776, DOI: 10.1016/s0165-3806(99)00183-2.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic AgonistsAnimalsBiological TransportBlood-Brain BarrierCatecholaminesCell FractionationCells, CulturedChick EmbryoChromatography, GelCulture Media, ConditionedDopamine AgonistsElectric ImpedanceEndopeptidasesEye ProteinsIndolesPigment Epithelium of EyeSerotonin Receptor AgonistsTight JunctionsConceptsRetinal pigment epitheliumBlood-retinal barrierTransepithelial electrical resistanceOuter blood-retinal barrierBlood-brain barrierEffects of astrocytesCultured retinal pigment epitheliumChick retinal pigment epitheliumPigment epitheliumNeural retinaRetinal factorsChick retinaRPE barrierRPE cellsRetinaEndothelial regionAstrocytesTight junctionsCulture modelDiffusible factorsDifferent stagesActive factorsJunction developmentMultistep processFactors