2024
Comparative analysis of patients with new onset refractory status epilepticus preceded by fever (febrile infection‐related epilepsy syndrome) versus without prior fever: An interim analysis
Jimenez A, Gopaul M, Asbell H, Aydemir S, Basha M, Batra A, Damien C, Day G, Eka O, Eschbach K, Fatima S, Fields M, Foreman B, Gerard E, Gofton T, Haider H, Hantus S, Hocker S, Jongeling A, Aparicio M, Kandula P, Kang P, Kazazian K, Kellogg M, Kim M, Lee J, Marcuse L, McGraw C, Mohamed W, Orozco J, Pimentel C, Punia V, Ramirez A, Steriade C, Struck A, Taraschenko O, Treister A, Yoo J, Zafar S, Zhou D, Zutshi D, Gaspard N, Hirsch L, Hanin A. Comparative analysis of patients with new onset refractory status epilepticus preceded by fever (febrile infection‐related epilepsy syndrome) versus without prior fever: An interim analysis. Epilepsia 2024, 65: e87-e96. PMID: 38625055, DOI: 10.1111/epi.17988.Peer-Reviewed Original ResearchFebrile infection-related epilepsy syndromeRefractory status epilepticusMacrophage inflammatory protein-1 alphaOnset refractory status epilepticusStatus epilepticusCerebrospinal fluidFIRES patientsCerebrospinal fluid interleukin-6Magnetic resonance imaging findingsComparative analysis of patientsAnalysis of patientsChemokine ligand 2Presenting symptomsFebrile infectionsClinical featuresGastrointestinal prodromeImaging findingsInflammatory biomarkersAntiseizure medicationsInterleukin-6Epilepsy syndromesInterim analysisPatientsEpilepticusFever
2019
New onset refractory status epilepticus research: What is on the horizon?
Gofton TE, Gaspard N, Hocker SE, Loddenkemper T, Hirsch LJ. New onset refractory status epilepticus research: What is on the horizon? Neurology 2019, 92: 802-810. PMID: 30894443, DOI: 10.1212/wnl.0000000000007322.Peer-Reviewed Original ResearchConceptsNew-onset refractory status epilepticusRefractory status epilepticusStatus epilepticusFebrile infection-related epilepsy syndromeMore rescue medicationsRescue medicationNew onsetActive epilepsyClinical featuresClinical presentationEpilepsy syndromesMetabolic causesNeurologic disordersPediatric EvaluationSpecific diagnosisAge groupsEpilepticusFamily supportFuture collaborative researchMedicationsPatientsFeverEpilepsyPathophysiologySyndrome
2008
Updates in the Management of Seizures and Status Epilepticus in Critically Ill Patients
Khaled K, Hirsch LJ. Updates in the Management of Seizures and Status Epilepticus in Critically Ill Patients. Neurologic Clinics 2008, 26: 385-408. PMID: 18514819, DOI: 10.1016/j.ncl.2008.03.017.Peer-Reviewed Original ResearchConceptsStatus epilepticusIll patientsManagement of seizuresOrgan transplant patientsRenal failure patientsReversal of factorsFirstline treatmentSystemic sequelaeTransplant patientsAntiseizure medicationsFailure patientsSeizure thresholdEarly recognitionElectroencephalogram monitoringMaximal responseSpecific treatmentPatientsMetabolic imbalanceEpilepticusMedicationsSeizuresTreatmentSequelaeFeverHypoxia
2006
Advances in the Management of Seizures and Status Epilepticus in Critically Ill Patients
Khaled K, Hirsch LJ. Advances in the Management of Seizures and Status Epilepticus in Critically Ill Patients. Critical Care Clinics 2006, 22: 637-659. PMID: 17239748, DOI: 10.1016/j.ccc.2006.06.004.Peer-Reviewed Original ResearchConceptsStatus epilepticusIll patientsAnti-seizure medicationsFirst-line treatmentManagement of seizuresOrgan transplant patientsRenal failure patientsReversal of factorsSystemic sequelaeTransplant patientsFailure patientsSeizure thresholdEarly recognitionElectroencephalogram monitoringMaximal responseSpecific treatmentPatientsMetabolic imbalanceEpilepticusMedicationsSeizuresTreatmentSequelaeFeverHypoxia