2021
A systematic review of seizure clusters: Prevalence, risk factors, burden of disease and treatment patterns
Chung S, Szaflarski JP, Choi EJ, Wilson JC, Kharawala S, Kaur G, Hirsch LJ. A systematic review of seizure clusters: Prevalence, risk factors, burden of disease and treatment patterns. Epilepsy Research 2021, 177: 106748. PMID: 34521043, DOI: 10.1016/j.eplepsyres.2021.106748.Peer-Reviewed Original ResearchConceptsSeizure action planRescue medicationSeizure clustersStatus epilepticusTreatment patternsSeizure remissionTreatment resistanceHigh riskPoor physician-patient communicationSeizure-related hospitalizationHigh seizure frequencyBurden of diseaseProductivity of patientsPhysician-patient communicationNon-SC patientsQuality of lifeSystematic literature searchConsecutive seizuresSeizure frequencyTreatment guidelinesProspective studySC patientsCaregiver QOLDisease burdenRisk factors
2016
Treatment of Convulsive Status Epilepticus
Grover EH, Nazzal Y, Hirsch LJ. Treatment of Convulsive Status Epilepticus. Current Treatment Options In Neurology 2016, 18: 11. PMID: 26920416, DOI: 10.1007/s11940-016-0394-5.Peer-Reviewed Original ResearchAnti-epileptic drugsNon-convulsive SEStatus epilepticusRefractory SEPreferred second-line agentNon-convulsive status epilepticusAnti-seizure medicationsHome rescue medicationThird-line agentsAcute side effectsConvulsive status epilepticusFirst-line treatmentNon-convulsive seizuresSecond-line agentsLower health care costsEmergency room visitsImmuno-modulatory agentsRecovery of consciousnessUse of benzodiazepinesQuality of lifeHealth care costsConsecutive seizuresParaneoplastic etiologyRescue medicationBuccal midazolam