2023
Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2021
Left atrial evaluation by cardiovascular magnetic resonance: sensitive and unique biomarkers
Peters DC, Lamy J, Sinusas AJ, Baldassarre LA. Left atrial evaluation by cardiovascular magnetic resonance: sensitive and unique biomarkers. European Heart Journal - Cardiovascular Imaging 2021, 23: 14-30. PMID: 34718484, PMCID: PMC8685602, DOI: 10.1093/ehjci/jeab221.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementAtrial fibrillationCardiovascular magnetic resonanceDiastolic dysfunctionEjection fractionAF recurrenceAtrial fibrosisNew-onset atrial fibrillationPost-operative atrial fibrillationLongitudinal LA strainExtent of fibrosisLong-axis cine imagesCine imagesAtrial imagingCardiovascular eventsLA volumeRisk stratificationAF subjectsPrognostic informationHypertrophic cardiomyopathyLA strainGadolinium enhancementSensitive markerAblation proceduresMagnetic resonanceClinical Impact of Cardiovascular Magnetic Resonance in Cancer Patients With Suspected Cardiomyopathy
Heidari-Bateni G, Durand J, Iliescu C, Gladish G, Deswal A, Patel A, Kim P, Song J, Hassan S, Palaskas N, Baldassarre L, Bucciarelli-Ducci C, Lopez-Mattei J. Clinical Impact of Cardiovascular Magnetic Resonance in Cancer Patients With Suspected Cardiomyopathy. Frontiers In Cardiovascular Medicine 2021, 8: 734820. PMID: 34765654, PMCID: PMC8576269, DOI: 10.3389/fcvm.2021.734820.Peer-Reviewed Original ResearchLeft ventricular ejection fractionCardiovascular magnetic resonanceHigher left ventricular ejection fractionTertiary cancer centerCancer patientsClinical impactInfiltrative cardiomyopathyMultiple myelomaCancer CenterPresumptive diagnosisClinical diagnosisCardio-oncology practiceCancer diagnosisVentricular ejection fractionSignificant clinical impactClinical decision makingLogistic regression modelsBaseline characteristicsConsecutive patientsEjection fractionEndomyocardial biopsyDiverse etiologiesCMR resultsMagnetic resonancePatients57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity
Cuomo J, Ragheb E, Feher A, Kwan J, Huber S, Mojibian H, Peters D, Sinusas A, Baldassarre L. 57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity. Journal Of Clinical And Translational Science 2021, 5: 141-142. PMCID: PMC8827987, DOI: 10.1017/cts.2021.761.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsVentricular ejection fractionLV strainCardiotoxicity groupCheckpoint inhibitorsEjection fractionProspective studyCardiac functionNormal left ventricular ejection fractionLeft ventricular ejection fractionCardiac magnetic resonance imagingCardiac magnetic resonance imaging techniquesGlobal longitudinal LV strainAbnormal troponin valuesEvidence of cardiotoxicityProportion of myocardiumLarge prospective studiesLongitudinal LV strainStudy of patientsSteady-state free precession cine imagesAbnormal cardiac functionCircumferential LV strainT2-weighted imagingMagnetic resonance imagingDysfunctional segments
2020
Clinical and Advanced MRI Techniques for Detection of Checkpoint Inhibitor Associated Myocarditis
Arbune A, Soufer A, Baldassarre L. Clinical and Advanced MRI Techniques for Detection of Checkpoint Inhibitor Associated Myocarditis. Current Cardiovascular Imaging Reports 2020, 13: 3. DOI: 10.1007/s12410-019-9521-5.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsEndomyocardial biopsyAdverse eventsCases of ICIImmune-related adverse eventsCardiac magnetic resonance imagingImmune adverse eventsDiagnosis of myocarditisBiventricular ejection fractionAdvanced MRI techniquesInvasive endomyocardial biopsyMagnetic resonance imagingPurpose of ReviewWithGold standard testAssociated myocarditisCheckpoint inhibitorsCMR findingsMyocardial inflammationEjection fractionSerial monitoringNoninvasive testsPrognostic informationTissue characterization informationCardiac biomarkersParametric mapping techniques
2019
CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION
Kwan J, Arbune A, Henry M, Dupee D, Soufer A, Baldassarre L. CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION. Journal Of The American College Of Cardiology 2019, 73: 1666. DOI: 10.1016/s0735-1097(19)32272-7.Peer-Reviewed Original ResearchMyocarditis with checkpoint inhibitor immunotherapy: case report of late gadolinium enhancement on cardiac magnetic resonance with pathology correlate
Gallegos C, Rottmann D, Nguyen VQ, Baldassarre LA. Myocarditis with checkpoint inhibitor immunotherapy: case report of late gadolinium enhancement on cardiac magnetic resonance with pathology correlate. European Heart Journal - Case Reports 2019, 3: yty149. PMID: 31020225, PMCID: PMC6439394, DOI: 10.1093/ehjcr/yty149.Peer-Reviewed Case Reports and Technical NotesLate gadolinium enhancementCardiovascular magnetic resonanceCardiac complicationsGadolinium enhancementAnti-programmed cell death protein 1 monoclonal antibodyCell death protein 1 monoclonal antibodyLeft ventricular ejection fractionNon-ischemic patternAcute heart failureCheckpoint inhibitor therapyRefractory cardiogenic shockCarotid artery dissectionCheckpoint inhibitor immunotherapyVentricular ejection fractionArea of myocardiumCardiac magnetic resonanceDirect histological correlationAreas of LGEArtery dissectionCardiogenic shockCheckpoint inhibitorsImmunosuppressive therapyVentricular dysfunctionEjection fractionHeart failurePrognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history