2024
Adverse social determinants of health elevate uncontrolled hypertension risk: a cardio-oncology prospective cohort study
Nain P, Stabellini N, Makram O, Rast J, Yerraguntla S, Gopu G, Bhave A, Seth L, Patel V, Jiang S, Malik S, Shetewi A, Montero A, Cullen J, Agarwal N, Wang X, Ky B, Baldassarre L, Weintraub N, Harris R, Guha A. Adverse social determinants of health elevate uncontrolled hypertension risk: a cardio-oncology prospective cohort study. JNCI Cancer Spectrum 2024, 8: pkae064. PMID: 39115393, PMCID: PMC11368120, DOI: 10.1093/jncics/pkae064.Peer-Reviewed Original ResearchSocial determinants of healthSocial determinants of health scoreSocial determinantsAdverse SDHImpact of social determinants of healthUncontrolled hypertensionAdverse social determinantsDeterminants of healthRisk of uncontrolled hypertensionProspective cohort studyCardio-oncology clinicCancer patientsBlood pressure readingsHypertension riskHypertension controlCohort studySocial isolationUrban residentsClinic blood pressure readingsControlled hypertensionIncreased riskProspective study patientsCox regressionCardio-oncologyHealth
2023
Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients
Kwan J, Arbune A, Henry M, Hu R, Wei W, Nguyen V, Lee S, Lopez-Mattei J, Guha A, Huber S, Bader A, Meadows J, Sinusas A, Mojibian H, Peters D, Lustberg M, Hull S, Baldassarre L. Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients. PLOS ONE 2023, 18: e0286364. PMID: 37252927, PMCID: PMC10228774, DOI: 10.1371/journal.pone.0286364.Peer-Reviewed Original ResearchConceptsBreast cancer patientsSystolic heart failureCardiovascular outcomesCancer patientsHeart failureValvular diseaseStrain abnormalitiesLeft ventricular ejection fraction reductionCancer treatment-related cardiotoxicityCardiovascular magnetic resonance findingsVentricular ejection fraction reductionYale-New Haven HospitalEjection fraction reductionTreatment-related cardiotoxicityAdverse cardiovascular outcomesClinical risk factorsNormal LV functionGlobal longitudinal strainIschemic heart diseaseMagnetic resonance findingsRisk regression modelsNew Haven HospitalSubclinical cardiotoxicityDiastolic dysfunctionStatin useRacial and Ethnic Disparities in All-Cause and Cardiovascular Mortality Among Cancer Patients in the U.S.
Zhu C, Shi T, Jiang C, Liu B, Baldassarre L, Zarich S. Racial and Ethnic Disparities in All-Cause and Cardiovascular Mortality Among Cancer Patients in the U.S. JACC CardioOncology 2023, 5: 55-66. PMID: 36875907, PMCID: PMC9982284, DOI: 10.1016/j.jaccao.2022.10.013.Peer-Reviewed Original ResearchCVD mortalityYears of ageCancer patientsEthnic disparitiesHigh-risk cancer populationLong-term survivorship careNon-Hispanic Black individualsNH-White patientsEnd Results (SEER) databaseCardiovascular disease mortalityNH Asian/Pacific IslanderMost prevalent cancersAsian/Pacific IslandersAdjusted HRsPatients 18Cardiovascular mortalityClinical characteristicsLocalized cancerSurvivorship careWhite patientsResults databaseCancer populationCancer survivalDisease mortalityMalignancy diagnosis
2021
Cardiac Computed Tomography in Cardio-Oncology JACC: CardioOncology Primer
Lopez-Mattei JC, Yang EH, Ferencik M, Baldassarre LA, Dent S, Budoff MJ. Cardiac Computed Tomography in Cardio-Oncology JACC: CardioOncology Primer. JACC CardioOncology 2021, 3: 635-649. PMID: 34988472, PMCID: PMC8702811, DOI: 10.1016/j.jaccao.2021.09.010.Peer-Reviewed Original ResearchAtherosclerotic cardiovascular diseaseSubclinical atherosclerotic cardiovascular diseaseCancer patientsPericardial diseaseCardiac CTCancer treatment-related cardiovascular toxicityValvular heart diseaseCardiac computed tomographyCardiac magnetic resonanceCardiac tumorsCardiovascular complicationsCardiovascular riskCalcium scoreHeart failureNoncancer patientsCardiovascular toxicityHeart diseaseCardiovascular diseaseCT scanComputed tomographyPatientsRadiation therapy treatmentTherapy treatmentDiseaseNew subspecialtyClinical Impact of Cardiovascular Magnetic Resonance in Cancer Patients With Suspected Cardiomyopathy
Heidari-Bateni G, Durand J, Iliescu C, Gladish G, Deswal A, Patel A, Kim P, Song J, Hassan S, Palaskas N, Baldassarre L, Bucciarelli-Ducci C, Lopez-Mattei J. Clinical Impact of Cardiovascular Magnetic Resonance in Cancer Patients With Suspected Cardiomyopathy. Frontiers In Cardiovascular Medicine 2021, 8: 734820. PMID: 34765654, PMCID: PMC8576269, DOI: 10.3389/fcvm.2021.734820.Peer-Reviewed Original ResearchLeft ventricular ejection fractionCardiovascular magnetic resonanceHigher left ventricular ejection fractionTertiary cancer centerCancer patientsClinical impactInfiltrative cardiomyopathyMultiple myelomaCancer CenterPresumptive diagnosisClinical diagnosisCardio-oncology practiceCancer diagnosisVentricular ejection fractionSignificant clinical impactClinical decision makingLogistic regression modelsBaseline characteristicsConsecutive patientsEjection fractionEndomyocardial biopsyDiverse etiologiesCMR resultsMagnetic resonancePatients
2020
Cardiovascular Care of the Oncology Patient During COVID-19: An Expert Consensus Document From the ACC Cardio-Oncology and Imaging Councils
Baldassarre LA, Yang EH, Cheng RK, DeCara JM, Dent S, Liu JE, Rudski LG, Strom JB, Thavendiranathan P, Barac A, Zaha VG, Bucciarelli-Ducci C, Ellahham S, Deswal A, Lenneman C, Villarraga HR, Blaes AH, Ismail-Khan R, Ky B, Leja MJ, Scherrer-Crosbie M. Cardiovascular Care of the Oncology Patient During COVID-19: An Expert Consensus Document From the ACC Cardio-Oncology and Imaging Councils. Journal Of The National Cancer Institute 2020, 113: 513-522. PMID: 33179744, PMCID: PMC7717327, DOI: 10.1093/jnci/djaa177.Peer-Reviewed Original ResearchConceptsCardio-OncologyCardiovascular careCOVID-19Cardio-oncology patientsPrior cancer historyExpert consensus statementCoronavirus disease 2019 (COVID-19) pandemicExpert consensus documentRisk of infectionDisease 2019 pandemicCardiotoxicity surveillanceCardiovascular complicationsPericardial involvementLethal complicationCardiac dysfunctionOncology patientsRisk of exposureCancer historyCancer patientsCardiovascular diseaseConsensus statementAmerican CollegeCardiovascular treatmentConsensus documentPatientsOpportunities for improved cardiovascular disease prevention in oncology patients.
Bravo-Jaimes K, Marcellon R, Varanitskaya L, Kim PY, Iliescu C, Gilchrist SC, Baldassarre LA, Manisty C, Ghosh AK, Guha A, Lopez-Mattei JC. Opportunities for improved cardiovascular disease prevention in oncology patients. Current Opinion In Cardiology 2020, 35: 531-537. PMID: 32649353, DOI: 10.1097/hco.0000000000000767.Peer-Reviewed Original ResearchConceptsCardiovascular disease preventionCancer patientsDisease preventionCardiovascular disease prevention guidelinesCardiac risk factor modificationCancer treatmentCardiometabolic disease managementDisease prevention guidelinesCardiovascular risk factorsHigh cardiovascular riskRisk factor modificationAdverse cardiovascular outcomesRisk of cardiotoxicityOngoing clinical trialsNonpharmacologic therapiesCardiovascular eventsCardiovascular outcomesCardiovascular riskOncology patientsCancer survivorsPrevention guidelinesAdverse outcomesFactor modificationCardiorespiratory fitnessRisk factors
2019
CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION
Kwan J, Arbune A, Henry M, Dupee D, Soufer A, Baldassarre L. CARDIAC MAGNETIC RESONANCE IMAGING FEATURE TRACKING STRAIN AS A SENSITIVE MARKER OF CARDIOTOXICITY IN BREAST CANCER PATIENTS COMPARED WITH LEFT VENTRICULAR EJECTION FRACTION. Journal Of The American College Of Cardiology 2019, 73: 1666. DOI: 10.1016/s0735-1097(19)32272-7.Peer-Reviewed Original Research