Dendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study
Benson CA, Fenrich KK, Olson KL, Patwa S, Bangalore L, Waxman SG, Tan AM. Dendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study. Journal Of Neuroscience 2020, 40: 4297-4308. PMID: 32371602, PMCID: PMC7252482, DOI: 10.1523/jneurosci.2858-19.2020.Peer-Reviewed Original ResearchConceptsDendritic spine dynamicsInjury-induced painPeripheral nerve injuryNeuropathic painDorsal hornSpine dynamicsNerve injuryPeripheral nerve injury-induced painNerve injury-induced painSuperficial dorsal horn neuronsSpinal cord dorsal hornDorsal horn neuronsSuperficial dorsal hornMechanisms of painDendritic spine dysgenesisContext of injuryPostmortem tissue analysisSame dendritic branchRepeat imagingMale miceMedical conditionsEffective treatmentPainSpine dysgenesisDendritic spines