2022
Chapter 17 Approach to Follow Up After Ovarian Transplantation
Pacheco F, Oktay K. Chapter 17 Approach to Follow Up After Ovarian Transplantation. 2022, 177-184. DOI: 10.1016/b978-0-12-823344-3.00015-7.Peer-Reviewed Original ResearchGraft functionOvarian transplantationAcute postoperative phaseImmediate postoperative complicationsMedical specialistsLong-term careWay pregnancyPostoperative complicationsPostoperative periodTransplantation recipientsIVF attemptsPharmacological supportPostoperative phasePregnancy attemptsOvarian functionPreoperative preparationSimple surgeryNumerous medical problemsClose monitoringPatient's diseaseRecurrence riskMedical problemsTransplantationDiseaseMethod of choice
2021
Ovarian transplantation with robotic surgery and a neovascularizing human extracellular matrix scaffold: a case series in comparison to meta-analytic data
Oktay K, Marin L, Bedoschi G, Pacheco F, Sugishita Y, Kawahara T, Taylan E, Acosta C, Bang H. Ovarian transplantation with robotic surgery and a neovascularizing human extracellular matrix scaffold: a case series in comparison to meta-analytic data. Fertility And Sterility 2021, 117: 181-192. PMID: 34801235, PMCID: PMC8863399, DOI: 10.1016/j.fertnstert.2021.08.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCohort StudiesCryopreservationExtracellular MatrixFemaleFertility PreservationHumansMeta-Analysis as TopicNeovascularization, PhysiologicOvaryPregnancyPregnancy RateRetrospective StudiesRobotic Surgical ProceduresTissue Culture TechniquesTissue ScaffoldsTransplantation, AutologousYoung AdultConceptsGraft longevityCase seriesOvarian functionLow-dose aspirinOvarian tissue transplantationOvarian cortical piecesLower embryo qualityOocytes/embryosNeonatal outcomesTransdermal estrogenChemotherapy exposureOvarian transplantationCortical piecesMeta-analytic dataLower abdomenHealthy childrenLive birthsMAIN OUTCOMEGraft vascularizationExtracellular matrix scaffoldsOvarian tissueAneuploidy rateFunction returnsEmbryo qualityMeta-analytic update
2018
Ovarian tissue cryopreservation and transplantation
Bedoschi G, Oktay K. Ovarian tissue cryopreservation and transplantation. 2018, 148-152. DOI: 10.1201/9781351141680-19.Peer-Reviewed Original ResearchOvarian tissue cryopreservationOvarian cortical piecesFertility preservationAdvanced treatment strategiesOvarian transplantationCortical piecesOvarian stimulationSurvival outcomesOvarian functionTreatment strategiesTissue cryopreservationAccelerated phaseEarly detectionHeterotopic ovarian transplantationFertility preservation proceduresLower abdominal wallFirst descriptionOvarian endocrineInitial ischemiaOvarian cryopreservationPharmacological supportTransplant proceduresFollicle lossCancer careCancer patients
2016
Current succes and efficiency of autologous ovarian transplantation with cryopreserved tissue: a meta-analysis
Oktay K, Pacheco F. Current succes and efficiency of autologous ovarian transplantation with cryopreserved tissue: a meta-analysis. Fertility And Sterility 2016, 106: e131-e132. DOI: 10.1016/j.fertnstert.2016.07.392.Peer-Reviewed Original Research
2010
Improving autologous ovarian transplantation with frozen-banked tissue: robotic assistance and the utilization of a human regenerative matrix
Oktay K, Soleimani R, Lee S, Ozkavukcu S, Brito M, Babayev S. Improving autologous ovarian transplantation with frozen-banked tissue: robotic assistance and the utilization of a human regenerative matrix. Fertility And Sterility 2010, 94: s89. DOI: 10.1016/j.fertnstert.2010.07.344.Peer-Reviewed Original ResearchAutologous ovarian transplantationOvarian transplantationRobotic assistanceRegenerative matrixTransplantation
2004
Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue
Oktay K, Buyuk E, Veeck L, Zaninovic N, Xu K, Takeuchi T, Opsahl M, Rosenwaks Z. Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue. Obstetrical & Gynecological Survey 2004, 59: 520-522. DOI: 10.1097/00006254-200407000-00018.Peer-Reviewed Original ResearchOvarian cortical piecesOvarian stimulationCortical piecesOvarian tissueOvarian functionEndocrine functionFollicle-stimulating hormone increaseFrozen-thawed ovarian tissueSequelae of chemotherapyHuman menopausal gonadotropinFollicle-stimulating hormoneOvarian endocrine functionLower abdominal wallRecombinant human chorionic gonadotropinHuman chorionic gonadotropinIntracytoplasmic sperm injectionGonadotoxic chemotherapyMenopausal gonadotropinMost patientsOocyte retrievalOvarian transplantationPremature menopauseOocyte maturityPatient's uterusAbstract Patients
2002
The potential of ovarian tissue transplant to preserve fertility
Buyuk E, Oktay K. The potential of ovarian tissue transplant to preserve fertility. Expert Opinion On Biological Therapy 2002, 2: 361-370. PMID: 11955275, DOI: 10.1517/14712598.2.4.361.Peer-Reviewed Original ResearchConceptsClinical studiesOvarian tissue transplantsSafety of pregnancyFuture clinical trialsPremature ovarian failureOvarian follicle developmentOvarian graftsOvarian cryopreservationOvarian transplantationOvarian functionCancer patientsOvarian failureClinical trialsAnimal studiesTissue transplantsOvarian tissueFurther basic researchHormone productionFollicle developmentRevascularisation processPregnancyPatientsTransplantationWomenSafetyPreliminary Experience with Orthotopic and Heterotopic Transplantation of Ovarian Cortical Strips
Oktay K, Yih M. Preliminary Experience with Orthotopic and Heterotopic Transplantation of Ovarian Cortical Strips. Seminars In Reproductive Medicine 2002, 20: 063-074. PMID: 11941536, DOI: 10.1055/s-2002-23520.Peer-Reviewed Original ResearchConceptsOvarian cortical stripsOvarian transplantationOvarian tissueCortical stripsHeterotopic transplantationAutologous ovarian transplantationFrozen ovarian tissueHeterotopic techniqueNew York surgeonPatient selectionOvarian functionSurgical techniqueTransplantationTransplanted tissuePreliminary experienceExperimental modelOperating roomCancer cellsClinical applicationTissueSafety measuresOrthotopicCliniciansSurgeonsTrounson
2001
Recent progress in oocyte and ovarian tissue cryopreservation and transplantation
Oktay K, Kan M, Rosenwaks Z. Recent progress in oocyte and ovarian tissue cryopreservation and transplantation. Current Opinion In Obstetrics & Gynecology 2001, 13: 263-268. PMID: 11396648, DOI: 10.1097/00001703-200106000-00003.Peer-Reviewed Original ResearchConceptsOvarian tissue cryopreservationOocyte freezingTissue cryopreservationOocyte cryopreservationOvarian tissueOvarian stimulation cyclesGroup of patientsNumber of pregnanciesInstitutional review boardOvarian transplantationAge-related declineOvarian functionStimulation cyclesReproductive surgeryContext of cancerCryopreserved oocytesReproductive functionEmbryo freezingTransplantationReview boardFirst caseInadequate timeSignificant scientific advancesWomenOocytes
2000
Ovarian cryopreservation and transplantation: basic aspects
Oktay K, Karlikaya G, Aydin B. Ovarian cryopreservation and transplantation: basic aspects. Molecular And Cellular Endocrinology 2000, 169: 105-108. PMID: 11155939, DOI: 10.1016/s0303-7207(00)00361-0.Peer-Reviewed Original ResearchTransplantation of cryopreserved human ovarian tissue results in follicle growth initiation in SCID mice
Oktay K, Newton H, Gosden R. Transplantation of cryopreserved human ovarian tissue results in follicle growth initiation in SCID mice. Fertility And Sterility 2000, 73: 599-603. PMID: 10689020, DOI: 10.1016/s0015-0282(99)00548-8.Peer-Reviewed Original ResearchConceptsOvarian tissueSCID miceFrozen-thawed human ovarian tissueFrozen-thawed ovarian tissueAutologous ovarian transplantationFrozen-thawed graftsHuman ovarian tissueFollicle growth initiationLong-term survivalWeeks of graftingHuman primordial folliclesFollicle countOvarian transplantationImmunodeficiency miceMAIN OUTCOMEHealthy folliclesPrimordial folliclesAcademic centersAnimal studiesFollicle stageAdvanced folliclesFolliclesGraftMiceNecrotic cells