2007
A novel xenograft model to test the ovarian toxicity of chemotherapy agents in women
Oktay K, Oktem O. A novel xenograft model to test the ovarian toxicity of chemotherapy agents in women. Journal Of Clinical Oncology 2007, 25: 19504-19504. DOI: 10.1200/jco.2007.25.18_suppl.19504.Peer-Reviewed Original ResearchXenograft modelFollicle lossClinical trialsChemotherapy agentsHuman ovarian xenograft modelPrimordial follicle countsNovel xenograft modelOvarian xenograft modelOvarian reserveFollicle countMice 12Ovarian toxicityCY injectionGonadotoxic effectsPremenopausal femalesSingle doseHuman ovaryOvarian piecesClinical studiesImmunodeficient miceSingle injectionNew agentsOvarian histologyXenograft vasculatureTUNEL staining
2000
Ovarian cryopreservation and transplantation: basic aspects
Oktay K, Karlikaya G, Aydin B. Ovarian cryopreservation and transplantation: basic aspects. Molecular And Cellular Endocrinology 2000, 169: 105-108. PMID: 11155939, DOI: 10.1016/s0303-7207(00)00361-0.Peer-Reviewed Original Research
1998
Development of human primordial follicles to antral stages in SCID/hpg mice stimulated with follicle stimulating hormone.
Oktay K, Newton H, Mullan J, Gosden R. Development of human primordial follicles to antral stages in SCID/hpg mice stimulated with follicle stimulating hormone. Human Reproduction 1998, 13: 1133-1138. PMID: 9647533, DOI: 10.1093/humrep/13.5.1133.Peer-Reviewed Original ResearchConceptsWeeks of graftingSevere combined immunodeficiencyFollicle growthOvarian xenograftsAntral stageOestradiol levelsLong-term graftHuman ovarian xenograftsHuman follicle developmentHuman ovarian tissueOvarian follicular growthPreantral follicle growthLong-term graftingGranulosa cell layerHuman primordial folliclesCell nuclear antigenFSH administrationHpg miceKidney capsuleGonadotrophin stimulationRenal capsuleHuman ovaryImmunodeficient miceFollicular growthSmall follicles