2002
The potential of ovarian tissue transplant to preserve fertility
Buyuk E, Oktay K. The potential of ovarian tissue transplant to preserve fertility. Expert Opinion On Biological Therapy 2002, 2: 361-370. PMID: 11955275, DOI: 10.1517/14712598.2.4.361.Peer-Reviewed Original ResearchConceptsClinical studiesOvarian tissue transplantsSafety of pregnancyFuture clinical trialsPremature ovarian failureOvarian follicle developmentOvarian graftsOvarian cryopreservationOvarian transplantationOvarian functionCancer patientsOvarian failureClinical trialsAnimal studiesTissue transplantsOvarian tissueFurther basic researchHormone productionFollicle developmentRevascularisation processPregnancyPatientsTransplantationWomenSafety
2001
Ovarian tissue cryopreservation and transplantation: preliminary findings and implications for cancer patients
Oktay K. Ovarian tissue cryopreservation and transplantation: preliminary findings and implications for cancer patients. Human Reproduction Update 2001, 7: 526-534. PMID: 11727860, DOI: 10.1093/humupd/7.6.526.Peer-Reviewed Original ResearchConceptsOvarian tissue cryopreservationTissue cryopreservationYoung womenFrozen-banked ovarian tissueBone marrow transplantationCancers of childrenAntral follicle developmentAggressive chemotherapyComplete remissionCancer treatment modalitiesMarrow transplantationBenign causesCancer patientsTreatment modalitiesTransplantation trialsFresh graftsXenograft studiesRodent studiesOocyte cryopreservationOvarian tissuePatientsFollicle developmentTransplantationCancer treatmentWomenA technique for laparoscopic transplantation of frozen-banked ovarian tissue
Oktay K, Aydin B, Karlikaya G. A technique for laparoscopic transplantation of frozen-banked ovarian tissue. Fertility And Sterility 2001, 75: 1212-1216. PMID: 11384651, DOI: 10.1016/s0015-0282(01)01776-9.Peer-Reviewed Original ResearchConceptsFrozen-banked ovarian tissueLaparoscopic transplantationOvarian tissueAcademic medical centerSlow-freezing techniqueMenopausal gonadotropinOvarian stimulationSpontaneous mensesOvarian fossaPelvic peritoneumOvarian functionLaparoscopic techniqueOvarian cortexMedical CenterMAIN OUTCOMEMicrosurgical reconstructionProgesterone productionBlood flowFollicle developmentTransplantationPatientsTissueMensesGonadotropinTransplant
2000
Interaction of Extracellular Matrix and Activin-A in the Initiation of Follicle Growth in the Mouse Ovary1
Oktay K, Karlikaya G, Akman O, Ojakian G, Oktay M. Interaction of Extracellular Matrix and Activin-A in the Initiation of Follicle Growth in the Mouse Ovary1. Biology Of Reproduction 2000, 63: 457-461. PMID: 10906050, DOI: 10.1095/biolreprod63.2.457.Peer-Reviewed Original ResearchConceptsFollicle growth initiationFollicle developmentFollicle growthFollicle growth rateFollicle densityRecombinant human activinEarly follicle developmentEarly follicular developmentRole of activinAbsence of activinTotal folliclesFollicular growthExtracellular matrixFollicular developmentTreatment groupsMultilayer folliclesMouse ovariesActivin treatmentHuman activinPresence of lamininActivinExtracellular matrix componentsPrecise mechanismMiceFollicles
1997
Ontogeny of Follicle-Stimulating Hormone Receptor Gene Expression in Isolated Human Ovarian Follicles1
Oktay K, Briggs D, Gosden R. Ontogeny of Follicle-Stimulating Hormone Receptor Gene Expression in Isolated Human Ovarian Follicles1. The Journal Of Clinical Endocrinology & Metabolism 1997, 82: 3748-3751. PMID: 9360535, DOI: 10.1210/jcem.82.11.4346.Peer-Reviewed Original ResearchConceptsMessenger ribonucleic acidPrimordial folliclesFollicle stageElective cesarean sectionHuman ovarian folliclesPreantral follicle developmentFSH receptor geneHormone receptor gene expressionReceptor gene expressionFollicle-stimulating hormone receptor gene expressionCesarean sectionRectus muscleHuman ovaryAntral folliclesFollicular growthFSH expressionHuman folliculogenesisOvarian folliclesOvarian tissueGranulosa cellsMultilaminar folliclesStromal tissueSingle follicleFollicle developmentFollicles