2024
Utility and Outcomes of Ovarian Tissue Cryopreservation and Transplantation for Gynecologic Cancers: A Systematic Review and Meta-analysis.
Erden M, Gayete-Lafuente S, Vural N, Oktay K. Utility and Outcomes of Ovarian Tissue Cryopreservation and Transplantation for Gynecologic Cancers: A Systematic Review and Meta-analysis. Obstetrics And Gynecology 2024 PMID: 39173181, DOI: 10.1097/aog.0000000000005708.Peer-Reviewed Original ResearchCryopreserved ovarian tissue transplantationOvarian tissue cryopreservationOvarian tissue transplantationTissue cryopreservationAutologous transplantationGynecologic cancerTissue transplantationOutcome of autologous transplantationPreserving ovarian functionCochrane Library databasesOvarian endocrine functionPooled-effect estimatesSystematic reviewRisk-of-bias assessmentOvarian stimulationHematologic malignanciesLonger-term outcomesFertility preservationOvarian functionBreast cancerLibrary databasesTransplantationGraft longevityCancerEndocrine function
2022
Female Infertility
Oktay K, Taylan E. Female Infertility. 2022, 1376-1381. DOI: 10.1093/med/9780198870197.003.0165.Peer-Reviewed Original ResearchFertility preservationOvarian insufficiencyOvarian follicle reservePreservation of fertilityReproductive-age womenEffective treatment optionOvarian endocrine functionAntineoplastic treatmentSurgical interventionFollicle reserveTreatment optionsAge womenFemale infertilityEndocrine functionPsychosocial healthChromosomal disordersReproductive technologiesWomenImproved qualityModern healthcareIrreversible lossInfertilityInsufficiency
2021
Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time?
Oktay K, Marin L, Petrikovsky B, Terrani M, Babayev S. Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time? Trends In Molecular Medicine 2021, 27: 753-761. PMID: 33549473, PMCID: PMC8427891, DOI: 10.1016/j.molmed.2021.01.005.Peer-Reviewed Original ResearchConceptsOvarian tissue cryopreservationTissue cryopreservationHealthy womenFertility preservation proceduresOvarian endocrine functionRisk-benefit assessmentOvarian cryopreservationEndocrine functionMedical indicationsOvarian tissueReproductive agingReproductive medicinePreservation proceduresAmerican SocietyWomenPrime timeCryopreservationResearch guidelinesAutotransplantationMenopauseTransplantation
2019
Chapter 30 Autologous Transplantation of Human Ovarian Tissue
Taylan E, Oktay K. Chapter 30 Autologous Transplantation of Human Ovarian Tissue. 2019, 493-500. DOI: 10.1016/b978-0-12-813209-8.00030-3.Peer-Reviewed Original ResearchHuman ovarian tissueOvarian tissueAutologous transplantationFrozen-thawed human ovarian tissueOvarian tissue cryopreservationReproductive-age womenPremature ovarian failureOvarian reserveGonadotoxic therapyAntineoplastic treatmentGonadotoxic treatmentFertility preservationOvarian cortexOvarian failureAge womenReproductive surgeryTissue cryopreservationEndocrine functionPrimordial folliclesPrepubertal ageNononcological diseasesTransplantationTreatmentDiseaseTissue
2015
Ovarian Tissue Cryopreservation: Where Are We Now?
Bedoschi G, Oktay K. Ovarian Tissue Cryopreservation: Where Are We Now? 2015, 71-78. DOI: 10.1007/978-3-319-17849-3_6.Peer-Reviewed Original ResearchFertility preservationOvarian stimulationOvarian cortical piecesAdvanced treatment strategiesPre-pubertal childrenOvarian cryopreservationCortical piecesSurvival outcomesOvarian functionCancer careCancer patientsTreatment strategiesEndocrine functionOocyte cryopreservationAccelerated phaseEarly detectionCancer communityPatientsTransplantationFirst descriptionStimulationSufficient time periodChemotherapySuccessful restorationCancer
2005
Sustained Endocrine Function And Spontaneous Pregnancies After Subcutaneous Transplantation Of Cryopreserved Ovarian Tissue In Stem Cell Transplant Recipients
Oktay K, Oktem O. Sustained Endocrine Function And Spontaneous Pregnancies After Subcutaneous Transplantation Of Cryopreserved Ovarian Tissue In Stem Cell Transplant Recipients. Fertility And Sterility 2005, 84: s68. DOI: 10.1016/j.fertnstert.2005.07.162.Peer-Reviewed Original Research
2004
Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue
Oktay K, Buyuk E, Veeck L, Zaninovic N, Xu K, Takeuchi T, Opsahl M, Rosenwaks Z. Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue. Obstetrical & Gynecological Survey 2004, 59: 520-522. DOI: 10.1097/00006254-200407000-00018.Peer-Reviewed Original ResearchOvarian cortical piecesOvarian stimulationCortical piecesOvarian tissueOvarian functionEndocrine functionFollicle-stimulating hormone increaseFrozen-thawed ovarian tissueSequelae of chemotherapyHuman menopausal gonadotropinFollicle-stimulating hormoneOvarian endocrine functionLower abdominal wallRecombinant human chorionic gonadotropinHuman chorionic gonadotropinIntracytoplasmic sperm injectionGonadotoxic chemotherapyMenopausal gonadotropinMost patientsOocyte retrievalOvarian transplantationPremature menopauseOocyte maturityPatient's uterusAbstract Patients