tRNA splicing in yeast and wheat germ. A cyclic phosphodiesterase implicated in the metabolism of ADP-ribose 1“,2”-cyclic phosphate.
Culver G, Consaul S, Tycowski K, Filipowicz W, Phizicky E. tRNA splicing in yeast and wheat germ. A cyclic phosphodiesterase implicated in the metabolism of ADP-ribose 1“,2”-cyclic phosphate. Journal Of Biological Chemistry 1994, 269: 24928-24934. PMID: 7929175, DOI: 10.1016/s0021-9258(17)31479-5.Peer-Reviewed Original ResearchConceptsCyclic phosphodiesteraseTransfer RNA (tRNA) splicingWheat germWheat germ enzymeCyclic phosphateCyclic phosphodiesterase activityRNA splicingYeast SaccharomycesEndonucleolytic cleavageYeast enzymeSplice junctionsADP-riboseBiochemical characteristicsTRNAYeastDistinct preferenceDetectable activityPhosphate linkagePhosphodiesteraseEnzymeLigation resultsPhosphodiesterase activityRiboseMetabolismEukaryotes