2017
White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine
Morie KP, Yip SW, Zhai ZW, Xu J, Hamilton KR, Sinha R, Mayes LC, Potenza MN. White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine. Drug And Alcohol Dependence 2017, 174: 23-29. PMID: 28292689, PMCID: PMC5555052, DOI: 10.1016/j.drugalcdep.2017.01.011.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureSuperior longitudinal fasciculusPCE adolescentsCrossing-fiber modelsGroup differencesWhole-brain investigationNon-exposed youthWhole-brain analysisSignificant group differencesAltered white matter developmentLeft superior longitudinal fasciculusRisk-taking behaviorNeurobiological underpinningsWhite matter developmentWhite matter microstructureSubstance useWhite matter differencesWhite matter regionsAdolescentsDiffusion-weighted imaging dataCocaine exposureLongitudinal cohortBilateral cingulumCorpus callosumROI analysisGray‐matter relationships to diagnostic and transdiagnostic features of drug and behavioral addictions
Yip SW, Worhunsky PD, Xu J, Morie KP, Constable RT, Malison RT, Carroll KM, Potenza MN. Gray‐matter relationships to diagnostic and transdiagnostic features of drug and behavioral addictions. Addiction Biology 2017, 23: 394-402. PMID: 28150390, PMCID: PMC5538947, DOI: 10.1111/adb.12492.Peer-Reviewed Original Research
2016
Regulating task-monitoring systems in response to variable reward contingencies and outcomes in cocaine addicts
Morie KP, De Sanctis P, Garavan H, Foxe JJ. Regulating task-monitoring systems in response to variable reward contingencies and outcomes in cocaine addicts. Psychopharmacology 2016, 233: 1105-1118. PMID: 26861797, DOI: 10.1007/s00213-015-4191-8.Peer-Reviewed Original ResearchConceptsReward processingTask successConsummatory reward processingEvent-related potentialsSpeeded response taskValue of rewardsMeasures of anhedoniaCocaine usersNeural measuresReward contingenciesPredictive cuesReward motivationReward receiptReward outcomesTask contingenciesResponse taskActive cocaine abusersReward probabilityHedonic toneAnticipatory responsesVulnerability markerReward scheduleMonitoring deficienciesAnhedoniaReward
2014
Executive dysfunction and reward dysregulation: A high-density electrical mapping study in cocaine abusers
Morie KP, De Sanctis P, Garavan H, Foxe JJ. Executive dysfunction and reward dysregulation: A high-density electrical mapping study in cocaine abusers. Neuropharmacology 2014, 85: 397-407. PMID: 24911989, PMCID: PMC4385568, DOI: 10.1016/j.neuropharm.2014.05.016.Peer-Reviewed Original Research
2013
Intact inhibitory control processes in abstinent drug abusers (II): A high-density electrical mapping study in former cocaine and heroin addicts
Morie KP, Garavan H, Bell RP, De Sanctis P, Krakowski MI, Foxe JJ. Intact inhibitory control processes in abstinent drug abusers (II): A high-density electrical mapping study in former cocaine and heroin addicts. Neuropharmacology 2013, 82: 151-160. PMID: 23507565, DOI: 10.1016/j.neuropharm.2013.02.023.Peer-Reviewed Original Research