2019
Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins
Tingey M, Mudumbi KC, Schirmer EC, Yang W. Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins. International Journal Of Molecular Sciences 2019, 20: 5248. PMID: 31652739, PMCID: PMC6862087, DOI: 10.3390/ijms20215248.Peer-Reviewed Original ResearchConceptsNuclear envelope transmembrane proteinsEnvelope transmembrane proteinsInner nuclear membraneOuter nuclear membraneNuclear envelopeTransmembrane proteinDouble membraneNuclear membraneInner nuclear envelopeGenome architectureNuclear organizationNuclear positioningEukaryotic cellsCellular functionsDNA replicationEndoplasmic reticulumCorrect localizationProteinVital functionsMembraneNuclear structureImportant roleSplicingEpigeneticsNuclear stability
2017
Determination of Membrane Protein Distribution on the Nuclear Envelope by Single‐Point Single‐Molecule FRAP
Mudumbi K, Yang W. Determination of Membrane Protein Distribution on the Nuclear Envelope by Single‐Point Single‐Molecule FRAP. Current Protocols In Cell Biology 2017, 76: 21.11.1-21.11.13. PMID: 28862339, PMCID: PMC5879780, DOI: 10.1002/cpcb.27.Peer-Reviewed Original ResearchConceptsNuclear envelope transmembrane proteinsInner nuclear membraneOuter nuclear membraneNuclear membraneEnvelope transmembrane proteinsEukaryotic cellsTransmembrane proteinEndoplasmic reticulumHuman diseasesFluorescence recoveryTranslocation rateTranslocation dynamicsMembraneAbnormal distributionProteinReticulumMicroscopy techniquesCellsVivoSpatial distribution
2016
Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution
Mudumbi K, Schirmer E, Yang W. Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution. Nature Communications 2016, 7: 12562. PMID: 27558844, PMCID: PMC5007294, DOI: 10.1038/ncomms12562.Peer-Reviewed Original ResearchConceptsNuclear envelope transmembrane proteinsInner nuclear membraneOuter nuclear membraneNuclear membraneEnvelope transmembrane proteinsMembrane protein distributionTranslocation rateTransmembrane proteinEndoplasmic reticulumProtein distributionHuman diseasesMembraneProteinReticulumMicroscopy techniquesDetermination of distributionVivo