Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development
Iwaya T, Sawada G, Amano S, Kume K, Ito C, Endo F, Konosu M, Shioi Y, Akiyama Y, Takahara T, Otsuka K, Nitta H, Koeda K, Mizuno M, Nishizuka S, Sasaki A, Mimori K. Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development. International Journal Of Oncology 2016, 50: 441-447. PMID: 28035351, DOI: 10.3892/ijo.2016.3817.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinogenesisCarcinoma, Squamous CellChromosomes, Human, Pair 17Down-RegulationEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLoss of HeterozygosityMaleReal-Time Polymerase Chain ReactionSialyltransferasesTranscriptomeConceptsQuantitative real-time reverse transcription PCRSporadic esophageal squamous cell carcinomasResponsible geneRNA sequence analysisClinical ESCC samplesPutative tumor suppressor geneCell linesTumor suppressor geneChromosome 17q25.1Esophageal squamous cell carcinoma (ESCC) developmentReal-time reverse transcription PCREsophageal squamous cell carcinomaMultiple genesCandidate genesExpression patternsChromosome 17q25Reverse transcription-PCRSequence analysisSuppressor geneGenesMethylation analysisCorresponding normal tissuesST6GALNAC1Transcription-PCRESCC development